Influvac - instructions, application, indications, contraindications, action, side effects, analogues, composition, dosage. Trading House Allergen. Influvac.

When developing vaccinations, companies are guided by representatives of the flora of the previous year, taking into account possible mutations between themselves. Non-specific prophylaxis is aimed at preventing complications and eliminating a lethal outcome. With weak immunity, secondary bacterial infections appear: measles, diphtheria, poliomyelitis.

Statistics claim that annual vaccinations significantly reduce mortality and morbidity in the human population from seasonal infection. The influenza A pandemic was recorded in 2009. Due to the mutation of the pathogen, an atypical form arose, against which there were no antibodies. In people with stable immunity, a rapid increase in immunoglobulins was observed. Patients with weak protective complexes were unable to resist the infection, which led to a rapid death. medical supplies were ineffective due to the rapid destruction of the causative agent of the pulmonary alveoli.

Specific vaccination did not lead to the production of antibodies against the H1N1 serotype. The mass death of people from the influenza pandemic required the purchase by the Ministry of Health of the American drug Tamiflu. The drug is quite expensive, so it is not available for mass free distribution. A little later, a more affordable "arbidol" appeared. Russian production. It was recommended to be taken by doctors to prevent infection.

Influenza Vaccination Methods

The World Health Organization (WHO) recommends people over 65 years of age. Vaccination is recommended for all elderly patients with chronic diseases upper respiratory tract.

Children from 6 to 15 years old are also at risk of ARVI, so it is advisable to carry out daily prevention for them. Immunization is also carried out for women in the 2nd and 3rd trimesters of pregnancy, as well as for the constant receipt of aspirin.

Adverse consequences in persons with somatic diseases on the background of colds also require prior protection.

Influenza vaccination should be given to secondary school students special institutions, staff of institutes, universities. Military units, barracks are a source of increased risk for colds.

Vaccination against influenza is based on the production of immunoglobulins against pathogen antigens - neuraminidase, hemagglutinin. When these proteins are destroyed, the virus has no way to replicate. The inability to reproduce leads to the destruction of the microorganism by protective complexes.

To form nonspecific immunity, influenza vaccination is carried out in the fall, before the start of the season for colds.

The flu vaccine contains a small dose of the pathogen, which forms a tense immunity. A low concentration of the virion does not cause disease. Every year a new vaccination is carried out, as the virus mutates. The transformation of the main antigens (hemagglutinin, neuraminidase) occurs annually or several times a year, which does not allow creating a single stable influenza vaccination.

Influenza vaccine - preparation for vaccination

The flu vaccine provides short-term immunity. The tool does not form protection against colds. Doctors prescribe antibiotics for an infection. The drugs do not act on the causative agent of the common cold, but prevent the addition of bacterial flora. The persistence of the pathogen inside the cells of the respiratory tract causes the accumulation of decay products, which become a breeding ground for bacteria. Antibiotics are prescribed to destroy them.

Preventing an epidemic can be prevented by timely vaccination against influenza. It must be carried out before the start of mass infection.

Preparation for vaccination includes a number of important procedures:

Exclusion of inflammatory diseases of the respiratory tract;
Do not visit places mass stay of people;
Rinse the nasal mucosa twice a day disinfectant solutions to remove microbes;
Treatment of diseases of internal organs.

With absence clinical symptoms respiratory diseases and following the above procedures, you can ensure that the flu vaccination will be successful.

The best flu vaccine

When choosing an influenza vaccine, consideration should be given to the types and types of these prophylactic agents.

Produced by cultivating the necessary viruses in chick embryo cell culture. This hides one of the contraindications to vaccination - an allergy to chicken protein. In such a situation, you can use Optaflu. The vaccine is being developed using the mattress culture method, which eliminates the need to use a chicken medium for growing viruses.

The low effectiveness of vaccination in 2009 is due to the drift of the pathogen. Periodically, qualitative leaps occur due to the mutation of the genetic apparatus. The global pandemic required the development of a new remedy directly against the background of the infection. After the liquidation of mass outbreaks, the warehouses of pharmaceutical companies accumulated a large number of funds that were not spent. The economic penalty from such a situation turned out to be colossal. The situation has allowed pharmaceutical companies to reconsider approaches to the quality and quantity of influenza vaccines.

It should be noted that during the production of vaccination there is a "guessing game". Pharmaceutical companies are trying in a complicated way to predict which pathogen will be active this season. In fairness, it should be noted that even with an incorrect definition of the pathogen, positive result from vaccination will be. Influenza vaccination stimulates the immune system, which will fight any foreign agent.

Flu vaccination: is it worth it?

Influenza vaccine contraindications:

Allergy with the previous administration of the drug;
Allergic reactions to chicken protein;
Exacerbation of chronic infections;
Heat.

Despite rare side effects, important features of the formation of nonspecific immunity from influenza infection can be distinguished:

Vaccination reduces mortality, reduces the risk of complications;
The safety of vaccinations has been verified by research and practical experience;
Reduces the risk of complications among healthy people in organized groups;
Prevents complications in the elderly.

Although there is an official approved form for refusing vaccinations, we do not recommend using the document. There is no harm from the vaccine, so it is better to protect yourself from certain serotypes of pathogens than not be able to effective treatment infections.

What is the best flu vaccine

For the specific prevention of influenza, 2 categories of vaccines are used:

Alive (weakened);
Inactivated.

Whole cell;
Split (split);
Subunit.

Split influenza vaccines contain internal and surface antigens. Inoculations are well cleaned by removing viral proteins and lipids.

Example of split vaccines:

Microgen (Russia);
Fluarix (Belgium);
Begrivak (Germany).

Subunit variants contain viral proteins (neuraminidase, hemagglutinin):

Grippol (Russia);
Influvac (Netherlands);
Agrippal (Italy).

Small children are not recommended to administer live whole cell vaccines. Means are characterized by high reactogenicity, provoke complications, post-vaccination reactions. Vaccinations have the ability to form stable immunity, but the possibilities for use are limited.

Subunit split systems do not cause complications. In practice, when using these systems, acceptable immunity is formed, which is sufficient to develop antiviral protection. There are fewer complications with the introduction of the drug. Split vaccines are less effective, so their use is limited to a temporary period. The beneficial effect of the remedy can only be counted on the season following the vaccination.

Pharmaceutical companies are looking for whole-cell vaccines with minimal side effects. In the production of funds, it is necessary to evaluate the ability to cause adverse reactions. Whole cell influenza vaccines in practice show high efficiency. If it is possible to stop their reactogenicity in children, a high-quality remedy will be created to protect against influenza infection.

Influvac - a modern flu vaccine

Influvac is a modern high-quality influenza vaccine containing purified antigens of group A and B viruses. The advantage of the product is a high degree of removal of foreign ingredients. The composition of the product is updated annually, so the quality of removing impurities is improved.

Persons with frequent illnesses respiratory organs;
Patients over 65 years of age;
With cardiovascular diseases;
Diabetes;
With immunodeficiencies (lymphoma, HIV, taking large doses of glucocorticoids (hormones of the adrenal cortex));
Children under 18 years of age on the background of treatment with acetylsalicylic acid preparations;
Pregnant women in the 2nd or 3rd trimester.

Based on the indications, the possibility of using the influenza vaccine influvac in immunocompromised patients is clearly seen.

The disadvantage of the vaccine is its price. The vaccine is not part of the drugs purchased by the Ministry of Health. The vaccine is often used by patients in private centers, as it has fewer side effects. The tool is not the best, but belongs to the category of fairly high-quality drugs.

French Vaxigrip flu vaccine

French-developed split vaccine Vaxigripp received good feedback people who used it for the prevention of SARS. When answering which is better, you can recommend this option.

The annual renewal of the composition allows the remedy to be constantly effective against seasonal influenza infections. Only 1.5% of people have non-dangerous complications:

Subfebrile fever;
Chills;
Headache.

The immunostimulatory effect of Vaxigripp is observed a few days after administration. The Russian version, Grippol or Grippol Plus, should not be ignored either. Split vaccines cost $5-7, which is affordable for every citizen of the country. The Ministry of Health is buying cheaper options. You can not say that they are better or worse, but they give more side effects.

To determine which flu shot is best, you should consult your doctor. Each option acts individually on the human body.

In conclusion, we describe a common variant of immunization against influenza by combining the vaccine with oscillococcinum. The drug belongs to the category of homeopathic remedies, has no side effects, can be used in children and pregnant women.

The mechanism of action of the drug against viruses is not known. Oscillococcinum is an immunostimulant that reduces the severity of complications after the introduction of any influenza vaccination.

The effectiveness and safety of vaccination has been time-tested. The introduction of the virus should not be feared, as it is weakened. Remember that vaccination can save lives, as effective medicines from acute respiratory viral infections does not exist.