Amoxicillin for sinusitis: instructions for use for adults - dosages. Antibacterial therapy for sinusitis Can sinusitis be treated with amoxicillin

Amoxicillin is a potent semi-synthetic antibiotic that belongs to the penicillin group. Its action is to destroy harmful bacteria that can cause inflammation in the sinuses. Amoxicillin is effective in the treatment of sinusitis due to its medicinal properties. More details about its application will be discussed in this article.

A broad-spectrum antibacterial drug that actively affects gram-positive and gram-negative microorganisms. Regular use of Amoxicillin leads to the destruction of microbes as a result of a violation of protein synthesis. But not all microorganisms are sensitive to this drug. Some of them secrete special enzymes that destroy the active substances of Amoxicillin.

Sinusitis is far from the only disease in which doctors prescribe Amoxicillin. It is also effective in the treatment of pharyngitis, otitis media, acute sinusitis and other otorhinolaryngological infections.

How does it work

When ingested, the active components of Amoxicillin negatively affect harmful microorganisms, including staphylococcus aureus, streptococcus, shigella, salmonella, and even E. coli. The drug has a strong bactericidal effect on the patient's body, which allows you to get rid of sinusitis in the shortest possible period of time.

On a note! In terms of its antibacterial properties, Amoxicillin is not inferior to more expensive and well-known analogues. Therefore, it is often prescribed by doctors for the treatment of various otorhinolaryngological infections.

Before using Amoxicillin, you should familiarize yourself with its features:

• when it enters the stomach, the drug is not completely destroyed, as can happen with other drugs. It enters the bloodstream, providing a therapeutic effect in just 1-1.5 hours;
• since eating does not affect the properties of the antibiotic in any way, it can be taken both before and after meals. As a rule, the doctor makes an individual appointment schedule for the patient;
• Depending on the individual characteristics of the patient, the doctor may increase or decrease the dosage of the drug. The weight of the patient must also be taken into account. For example, if the patient weighs 40-45 kg, then the doctor prescribes no more than 400 mg of the drug;
• the optimal time interval between doses of Amoxicillin is from 6 to 8 hours. By reducing this gap, you risk harming the body;
• to reduce the negative impact on the functioning of the gastrointestinal tract, doctors recommend taking the remedy not after, but during a meal;
• if there are problems with the work of the kidneys in a patient, the attending physician may make adjustments to the intervals between doses of the drug. This also applies to the dosage of the antibiotic;
• the use of Amoxicillin reduces the effectiveness of contraceptives produced in the form of tablets. Therefore, when having sex, it is necessary to use additional protective equipment;

  Safe sex is very important

• in rare cases, the treatment with Amoxicillin may cause deterioration of the patient's condition. This is due to the active growth of bacteria that are not exposed to the drug;
• taking antibacterial drugs, you can drive a car and other modes of transport.

The effect of gastric juice does not affect the medicinal properties of the drug in any way, therefore, after a few hours from the moment of administration, the agent accumulates in the patient's maxillary sinuses, exerting an antibacterial effect on the body. After that, Amoxicillin is excreted from the body along with bile.

Dosage principles

• the daily dose for adult patients and children over 10 years of age is 1500 ml. Doctors recommend dividing this amount into three equal doses to be taken throughout the day;
• in the treatment of sinusitis in children 5-10 years old, doctors prescribe 750 ml, that is, one capsule 3 times a day;
• Patients aged 2 to 5 years should not take capsules. They need to be given a suspension of 375 mg per day.

Amoxicillin - suspension

On a note! The duration of the therapeutic course with Amoxicillin is 7 days. In rare cases, the doctor may increase the course of treatment up to 10 days, but this is decided on an individual basis. All actions in this case must be agreed with the attending physician.

If the previous course of treatment showed a positive result, then as a continuation of the dynamics, the doctor may extend the treatment of sinusitis with Amoxicillin.

Side effects and contraindications

It has already been noted earlier that Amoxicillin is a potent drug, which can be taken only under the supervision of the attending physician. Despite its effectiveness, this drug has a number of contraindications.

The main restrictions include:

• the presence of enteritis, colitis or severe dysbacteriosis;
• bowel disease;
• poor blood clotting;
• liver or kidney failure;
• allergy;
• Infectious mononucleosis;
• individual characteristics of the body.

These contraindications cannot be ignored, since this can lead to the fact that the patient will not only not be able to get rid of sinusitis, but will also harm his health even more. Many expectant mothers are afraid that it is absolutely impossible to take Amoxicillin during pregnancy. But in fact, this is not so, because doctors often prescribe a medicine during the period of bearing a child, especially if the risk to the fetus is small. In this case, the course of treatment should be under the strict supervision of the attending physician.

A feature of Amoxicillin is also that it can pass into breast milk, so it is not used during lactation. If the doctor still prescribed antibiotics to the nursing mother, then it is advisable to refuse breastfeeding for the period of therapy. For such cases, you can give other types of milk, for example, cow's. There are also special baby formulas that can be purchased at the store. They contain a sufficient amount of useful vitamins and minerals for the normal growth and development of the baby.

What are the analogues

For the treatment of sinusitis, not only Amoxicillin is used. For this purpose, doctors also use other antibacterial drugs that are not inferior in effectiveness. Below are analogues with which you can eliminate the symptoms of this pathology.

Table. Let's take antibiotics for sinusitis.

Name of the drug, photo	Description
	An effective antibacterial agent used in medicine to combat many pathogenic microbes. Unlike other drugs, Ceftriaxone causes almost no side effects, which makes it quite popular among patients.
	Another antibiotic used in medicine to treat sinusitis. Zitrolide does not provoke the development of toxic reactions in the patient's body. The agent actively fights gram-negative, gram-positive and anaerobic bacteria.
	A strong antibacterial agent belonging to the group of macrolipids. During treatment with Macropen, bacteria that actively multiply on the mucous membrane are destroyed. This contributes to the rapid recovery of the patient after suffering sinusitis.
	This drug has a bactericidal effect on the body. Its action begins when the focus of inflammation is filled with a special medicinal substance, which is part of the antibacterial drug. Azithromycin is effective in the treatment of sinusitis.
	If most of the antibiotics presented above are available in the form of capsules or tablets, then Isofra is used to treat sinusitis in the form of a spray. The agent is sprayed in the area of ​​\u200b\u200bthe focus of inflammation, while destroying pathogenic microbes. Isofra has antibacterial properties, due to which the affected mucous membrane is quickly restored.
	The tool has anti-inflammatory and antibacterial properties, which makes it indispensable in the treatment of sinusitis. Regular use of Bioparox leads to the destruction of various types of bacteria and fungi at the local level.

On a note! If the use of one of these drugs did not give a positive effect, the doctor may change the therapy system or the drug itself. This is done to select the most effective remedy in the treatment of symptoms of sinusitis.

As a conclusion

First of all, you need to remember that antibacterial drugs are strong medications, so only the attending physician can decide on their use. The results of the tests, the patient's complaints and the general history should serve as a reason for the doctor to prescribe one or another drug.

It is strongly not recommended to self-medicate, especially when it comes to taking antibiotics. Therefore, if you want to get rid of the symptoms of sinusitis once and for all, self-administration of Amoxicillin and other drugs should be abandoned.

Video - Features of the treatment of sinusitis

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For the treatment of inflammation of the paranasal sinuses, in most cases, drugs are used that have a detrimental effect on pathogenic bacteria. Penicillin antibiotic Amoxicillin for sinusitis is a first-line drug, it is used to prevent and treat the disease in the first place.

The high efficacy of amoxicillin and its combinations with clavulanic acid allows it to remain one of the most commonly used drugs for several decades.

Amoxicillin- This is a semi-synthetic broad-spectrum antibacterial agent that belongs to the group of penicillins. It was discovered in the 60s of the XX century, when the most active antibiotic used for ENT infections was ampicillin. After 12 years of testing for safety and efficacy amoxicillin entered the market in the form of the drug Amoxil. This medicine immediately became more preferable for bacterial infections due to its high bioavailability.

With the help of amoxicillin, it is recommended to treat diseases of the respiratory system (sinusitis, pharyngitis, pneumonia, otitis media, tracheitis, etc.), the genitourinary system (including gonorrhea), bacterial inflammation of the meninges, and gastrointestinal infections caused by Escherichia coli.

By recommending amoxicillin for sinusitis, the otolaryngologist tries to strike at most possible pathogens of a bacterial infection. Only if the disease develops practically unchanged within a week, is it replaced with another beta-lactam antibiotic (2-3 generation cephalosporin) or a combination of a penicillin drug with additional components.

The advantage of this drug compared to other effective antibiotics (aminoglycosides, Clarithromycin) is the ability to use it during pregnancy. Reviews of doctors and numerous studies suggest that amoxicillin therapy for sinusitis is well tolerated by elderly patients and children. Sufficient safety of the drug has been confirmed for infants.

Despite the fact that the drug was launched on the market back in 1972, the treatment of sinusitis with amoxicillin is still relevant today. The developed resistance of some pathogenic microorganisms to the action of beta-lactam antibiotics is powerless against penicillinase inhibitors - for example, clavulanic acid. This substance binds the degrading enzyme, protecting amoxicillin from decay and ensuring the full effectiveness of the drug.

The action of the drug

The drug Amoxicillin, as well as Augmentin, Ospamox, Amosin, etc., contains the only active ingredient - amoxicillin trihydrate. The penicillin antibiotic disrupts the synthesis of peptidoglycan, an important component of the bacterial cell wall, causing the dissolution of pathogenic microflora. Amoxicillin is active against gram-positive and gram-negative aerobic microorganisms, which include staphylococci, streptococci, gonococci, meningococci, Escherichia coli, Shigella, Klebsiella, Salmonella and Shigella. Also, the drug is moderately effective against moraxella.

When taken orally, the active substance is quickly and almost completely (93%) adsorbed in the gastrointestinal mucosa. The resistance of amoxicillin to acid allows it to retain its properties, despite the action of gastric juice. The pharmacological effect of the drug occurs within 15-30 minutes after the use of tablets or capsules.

The duration of the period of antibacterial activity is about 8 hours. From this it follows that if you take an antibiotic for sinusitis - amoxicillin, then the daily dose of the drug will be divided into three doses to constantly maintain the optimal concentration of the substance.

Before taking amoxicillin for sinusitis, you must carefully read the instructions and contraindications. The dosage of the medicine is selected by the attending physician. With renal failure and taking a number of drugs, it may be necessary to reduce the amount of antibiotic recommended by the instruction for sinusitis.

Does amoxicillin help with sinusitis?

The development of acute bacterial sinusitis is often provoked by pneumococci, Haemophilus influenzae, Moraxella. Less commonly, the disease develops as a result of infection with pyogenic streptococcus, Staphylococcus aureus and other aerobic and anaerobic bacteria. In a chronic inflammatory process, pathogens are often several representatives of pathogenic microflora.

The cause of acute sinusitis often becomes a viral infection - in particular, influenza, corona-, rhino-, adenovirus and others. In diseases caused by these microorganisms, antibiotics are ineffective, but are often prescribed preventively. This is due to the fact that a viral infection located in a closed paranasal sinus, in the absence of treatment, in most cases is complicated by the active reproduction of pathogenic bacteria.

Once in the body, amoxicillin penetrates the tissues and accumulates in the secretion of the maxillary sinuses, realizing its pharmacological effect.

The antibacterial activity of amoxicillin extends to most strains of bacteria that can cause disease. According to American scientists who conducted a study of the activity of antibiotics in various diseases, the effectiveness of the treatment of sinusitis with tablets with a high dosage of amoxicillin averages 80-90%.

However, we should not forget that some strains of bacteria are resistant to the action of penicillin. These include 64% of pneumococcal strains, up to 90% of Staphylococcus aureus strains, and 27-43% of Haemophilus influenzae strains. In case of infection with these types of pathogens, it is necessary to take a protected dosage form of the drug, which contains not only amoxicillin, but also a penicillinase inhibitor (tazobactam, sulbactam or clavulanic acid).

How to take amoxicillin for sinusitis

Amoxicillin is available in several pharmacological forms:

• capsules of 250 mg and 500 mg;
• tablets of 125 mg, 250 mg, 500 mg and 1000 mg;
• granules for suspension (2.5% and 5%), 125 mg and 250 mg in 5 ml of solution;
• dry powder (1 g) for dilution with saline (preparation of the drug for injections and droppers).

The variety of forms of administration makes Amoxicillin available for use in the treatment of children, adults, the elderly and bedridden patients.

How much antibiotic to take for adults

The usual daily dosage for children over 12 years of age and adult patients is 1500 mg (500 mg every 8 hours). In complicated cases, the amount of antibiotic can be increased to 2.25-3 g per day. The maximum allowable safe daily dosage of amoxicillin is 6 g. The doctor should determine the dose and regimen of the drug.

Dosage of medication for children

Children under 5 years old Amoxicillin not prescribed in the form of tablets or capsules. For the treatment of pediatric sinusitis, doctors recommend only a suspension.

The optimal daily dosage for patients under 2 years of age is calculated based on the weight of the child: 20 mg of the active substance is taken per 1 kg of body weight. The resulting value is divided into 3 steps. The maximum daily dose should not exceed 375 mg of the drug, which corresponds to 7.5 ml of a 5% suspension or 15 ml of a 2.5% suspension.

Children 2-5 years of age are prescribed 125 mg of amoxicillin every 8 hours. Patients aged 5-12 years are prescribed tablets or capsules of 250 mg three times a day.

Duration of therapy

Therapy lasts an average of 5-12 days. The five-day period allows the doctor to evaluate the effectiveness of the drug and continue taking or change the antibiotic. After the disappearance of the symptoms of the disease, treatment should continue for another 2-3 days in order to consolidate the result and avoid a relapse of the disease.

Side effects and contraindications

Contrary to the fears of many patients, Amoxicillin has a fairly small number of side effects and contraindications.

The use of the drug is prohibited for such indications as:

• tendency to allergic reactions, hay fever, bronchial asthma;
• individual sensitivity to penicillin antibiotics (a cross-reaction to cephalosporins is also possible);
• enteritis, pseudomembranous colitis, severe intestinal dysbacteriosis;
• severe liver pathology;
• Infectious mononucleosis;
• lymphocytic leukemia.

Despite the safety of the drug, it is prescribed with caution during pregnancy, renal failure and bleeding disorders. With sinusitis in a nursing mother, it is advisable to stop breastfeeding for the entire time of taking Amoxicillin.

Side effects of penicillin antibiotic use include:

• allergic reactions (urticaria, rhinitis, erythema, angioedema, rarely - fever, joint pain, exudative erythema, etc.);
• dysbacteriosis;
• nausea, vomiting;
• diarrhea, enterocolitis;
• liver dysfunction;
• headache, dizziness;
• insomnia, anxiety;
• leukopenia, anemia, neuropenia, thrombocytopenia;
• difficulty breathing;
• tachycardia;
• candidiasis.

Patients with severe chronic diseases or reduced body resistance may develop superinfection - a condition in which inflammation is caused by a sharp increase in pathogens of a different type than the original one.

Side effects appear infrequently. In some cases, the cause of the pathological reaction is self-medication with an antibacterial drug and exceeding the recommended dosage. A qualified specialist should draw up a treatment regimen and select a dosage.

With the development of an allergic reaction or the manifestation of other side effects, it is necessary to stop taking the medicine and consult your doctor to select another antibiotic.

While taking Amoxicillin, the following aspects should be taken into account:

1. Influence of an antibiotic on efficiency of oral contraceptives. Amoxicillin reduces the effectiveness of OCs containing estrogen. During antibiotic therapy, it is necessary to use additional means of protection.
2. Interaction of the drug with other drugs. Amoxicillin increases the toxicity of methotrexate. May cause skin rash in combination with allopurinol.
3. Required duration of treatment. The duration of therapy should be at least 5-7 days. Stopping treatment may lead to a relapse of the disease. In chronic and complicated processes, therapy can last longer.
4. Monitoring during treatment and restoration of intestinal microflora. If amoxicillin therapy lasts longer than 5-7 days, monitoring of the hematopoietic system, liver and kidney function is recommended. After the end of antibiotic therapy, it is necessary to drink a course of probiotics to prevent dysbacteriosis.
5. Alcohol compatibility. Instructions for use do not provide for a categorical prohibition of alcoholic beverages during therapy. But it should be noted that alcohol (especially when taken simultaneously) significantly reduces the effectiveness of the drug, increasing its toxicity to the liver and the likelihood of side effects.

You can drink medications with amoxicillin before, during or after meals, but many experts recommend taking the pills before eating.

Amoxicillin is a broad-spectrum agent that is effective against pathogens of sinusitis. Implementation of the recommendations of the attending physician regarding antibiotic therapy, bed rest and good nutrition dramatically reduce the risk of complications or the transition of the infection to a chronic form.

Sinusitis is a common disease characterized by inflammation of the mucous membrane of the paranasal sinuses, resulting in a violation of the upper respiratory tract.

Constant pain localized in the maxillary region of the head, congestion of the nasal passages with the release of purulent mucus, accompanying symptoms (general weakness, hyperthermia, decreased sense of smell), disrupt the process of normal human life. According to these signs, we can say that the disease is actively progressing. Respiratory infections should be treated as soon as possible to avoid serious complications.

Description

Amoxicillin is a highly effective semi-synthetic penicillin antibiotic belonging to the penicillin group. Its action is aimed at the destruction of pathogenic microorganisms that are the causative agents of infection in the sinuses and respiratory tract. By inhibiting the activity of gram-negative and gram-positive microorganisms, it is a powerful broad-spectrum antibacterial agent.

Amoxicillin works well for:

• streptococci;
• staphylococci;
• gonococci;
• salmonella;
• klebsiella;
• hemophilic bacillus, etc.

The drug can be called an innovative development, due to its effectiveness and low cost compared to analog drugs, it is able to compete with more popular drug brands.

The detrimental effect of the enzymes of some bacteria has a destructive effect on the chemical formula of amoxicillin, so pathogenic microorganisms of this group become insensitive to this antibiotic.

Due to the resistance of the drug to the acidic environment of the stomach, rapid absorption, Amoxicillin with sinusitis does not dissolve in gastric juice, immediately penetrating to the site of infection. The drug is widely used in the treatment of otorhinolaryngological diseases (pharyngitis, acute sinusitis, otitis media, etc.).

Since laryngitis can develop under the influence of various pathogens, it is customary to prescribe Amoxicillin to eliminate the following causes:

• viral infections;
• damage to the body by a bacterial form of infection;
• injury to the nasal septum as a result of force;
• developing allergic reaction of the body caused by various irritants;
• inflammation of the mucous membrane of the nasal cavity due to work in harmful, dangerous working conditions associated with chemical reagents.

Amoxicillin is available in various forms: tablets (1.0 g), capsules (0.25 and 0.5 g), granules (5 ml - 0.125 g) for the preparation of a suspension, powder for the preparation of intramuscular injections (1.0 g).

The main active ingredient of the tablets is amoxicillin trihydrate.

Unlike the tablet form of release, additional components may be present in capsules and granules, but the main effect of the drug is similar.

Video

Amoxicillin

Action

When ingested, the active components are completely absorbed in the gastrointestinal tract in the shortest possible time. The drug is acid-resistant, the constituent substances actively interact with gastric juice, without being destroyed under its influence. This property allows you to quickly eliminate the symptoms of the inflammatory process, stopping the vital activity of harmful microorganisms. Due to the high antibacterial action of Amoxicillin, the treatment of sinusitis is carried out as soon as possible, 1-2 weeks.

The components of the antiseptic agent freely penetrate into the soft tissues and circulatory system of the body, accumulate in the mucous secretory fluid of the nasal cavity, stopping the vital activity of destructive bacteria.

Amoxicillin penetrates into the parenchyma of the liver, kidneys, and is excreted through the bladder. A certain amount of the substance can be found in breast milk, therefore, during lactation, the drug is taken strictly for medical reasons in a certain dosage.

The benefits of the drug

If we talk about how effective Amoxicillin is for sinusitis, according to doctors, the drug copes not only with purulent accumulation caused by a maxillary infection, but also with other ENT diseases. The antibiotic is characterized by a targeted action, destroying the atomic structure of pathogenic bacteria. As a result of a violation of the synthesis of protein shells of pathogenic microorganisms, the process of formation of new cellular structures of microbes is completely blocked.

The main benefits of Amoxicillin are:

• due to antibacterial properties, there is a high percentage of targeted action on many harmful microorganisms;
• convenient form of release allows you to accurately calculate the dosage in accordance with the individual treatment regimen;
• good absorption into the gastrointestinal tract allows for effective antibacterial treatment;
• reasonable price contributes to the qualitative replacement of more expensive analog drugs with Amoxicillin.

Despite the wide spectrum of action of the antibacterial drug, its use should be carried out strictly according to the doctor's prescription with strict adherence to the dosage.

Many are interested in how to take Amoxicillin for sinusitis? The main course of treatment of the disease with this antibiotic is 1 week. In some cases, treatment is increased to 10 - 12 days. How many days, and in what dosage to take the medicine, is determined by the attending physician. It should be noted that with a weak effect of Amoxicillin, it can be replaced with an analog drug.

To achieve the maximum therapeutic effect, the following instructions should be observed:

• you can take an antibiotic only as prescribed by a doctor;
• with an advanced form of the development of the disease, the course of treatment may exceed a week.

Dosage for children

Average rates of taking Amoxicillin in children:

• up to 2 years, a single dose is 20 mg per 1 kg of body weight in three divided doses;
• from 2 to 5 years, it is recommended to use a suspension of 125 mg three times a day;
• from 5 to 10 years - 250 ml capsules should be taken three times a day.

When calculating the dosage for children, more weight is given than the age of the patient. Therefore, treatment should be carried out strictly according to the doctor's prescription on an individual basis.

Dosage for adults

Amoxicillin for sinusitis in adults is used according to the following scheme:

• children over 10 years old and weighing over 40 kg, as well as adults with moderate severity of the disease, are shown to take 500 ml of syrup, which should be divided into three times a day;
• with complicated sinusitis, a single dose is 0.75 - 1.0 g three times a day.

For adults, most often the drug is administered intramuscularly, with a maximum daily dose of 6.0 g per day.

Is it possible for pregnant women

When a woman is in a state of pregnancy, her body undergoes multiple changes. Moreover, consumed foods, liquids, medicines enter the body of a baby in the womb. Therefore, the use of antibiotics during pregnancy is prescribed according to special indications.

It should be understood that intrauterine infection of the embryo with a bacterial infection can lead to the following consequences:

• pneumonia;
• damage to the central nervous system;
• violation of the general development of the embryo with irreversible consequences.

In such situations, taking Amoxicillin during pregnancy is a justified, necessary action.

Contraindications

Like any other drug, Amoxicillin has some contraindications. Its reception is prohibited with the following pathological changes in the body:

• individual intolerance to the components of the remedy;
• renal, hepatic insufficiency;
• skin allergic diseases;
• bronchial asthma;
• diseases of the gastrointestinal tract;
• infectious form of mononucleosis;
• oncology.

Side effects

It is urgent to change the treatment regimen if the patient experiences the following side effects:

• disorder of the digestive system (diarrhea, vomiting, constipation);
• the appearance of an allergic reaction on the skin, shortness of breath;
• an increase in the intensity of symptoms of purulent sinusitis;
• eye inflammation (conjunctivitis).

Potent antibiotics, one of which is Amoxicillin, help to stop the pathogenic microflora in a timely manner. Despite the rather rare cases of side effects, patients should listen to any changes in the body, immediately report this to the attending physician.

Ceftriaxone

Zitrolide

macrofoam

Azithromycin

Bioparox

On a note! If the use of one of these drugs did not give a positive effect, the doctor may change the therapy system or the drug itself. This is done to select the most effective remedy in the treatment of symptoms of sinusitis.

First of all, you need to remember that antibacterial drugs are strong medications, so only the attending physician can decide on their use. The results of the tests, the patient's complaints and the general history should serve as a reason for the doctor to prescribe one or another drug.

be healthy

It is strongly not recommended to self-medicate, especially when it comes to taking antibiotics. Therefore, if you want to get rid of the symptoms of sinusitis once and for all, self-administration of Amoxicillin and other drugs should be abandoned.

To treat inflammation of the maxillary sinuses, the doctor may prescribe a variety of medications. One of them may be Amoxicillin for sinusitis, which is considered very effective in the treatment of a disease with a bacterial nature. Its action is aimed at combating microorganisms that are causative agents of the inflammatory process in the sinuses.

The drug is a semi-synthetic antibiotic and belongs to the penicillin group, providing a fairly wide spectrum of activity (he successfully manages to cope not only with gram-positive, but also gram-negative microorganisms).

Features of the action are associated with the destruction of protein synthesis in the bacterial walls, as a result of which the bacteria die. This occurs under the influence of special enzymes - beta-lactamases, however, there are microorganisms that are not sensitive to these enzymes and, accordingly, the described antibiotic is useless in relation to them.

One of the features of this drug is its acid resistance, as well as the possibility of using it for the treatment of a wide variety of otolaryngological infections, including sinusitis.

Amoxicillin is a powerful antibiotic used to treat sinusitis.

Amoxicillin for sinusitis is taken orally and immediately after that it is absorbed by the digestive tract, but is not destroyed there due to its acid resistance.

Its penetration into the tissues and through the histohematological barriers occurs quite easily - accordingly, it also soon appears in the inflamed secret, bringing “order” there, that is:

• destroying harmful microorganisms;
• preventing their reproduction;
• improving local immunity.

A certain trace of the drug remains in breast milk if it is taken by a woman in the lactation period.

Partial biotransformation of the drug occurs in the liver, and its output is carried out through the kidneys and bile.

The action of Amoxicillin is associated with the destruction of pathogenic bacteria

The release of the described medicine is made in the form of tablets, capsules, as well as granules, from which a suspension is prepared. Less commonly, it can be used as a solution for intramuscular injections and even for a dropper.

The correct dosage of Amoxicillin for sinusitis is prescribed only by a doctor. This is influenced by a fairly large number of factors and parameters:

• age;
• allergic reactions;
• gender;
• individual intolerance;
• other personal characteristics.

Together with this remedy, other medicines are often prescribed, since it is possible to cope with inflammation of the maxillary sinuses only through complex therapy.

When using it is important to observe the correct dosage of the drug

Usually, the medicine is allowed to children who have already reached the age of two. If they have not yet turned five, it is prescribed in the form of a suspension: it is a powder that has a pleasant fruity smell and is diluted in chilled water.

• A maximum of 375 milligrams of such a suspension should be drunk per day, despite the fact that it is prescribed to take it three times.
• Children who are already five years old, but not yet ten, need to drink three times a day, 250-milligram tablet. The therapeutic course is a week, but if necessary, the doctor can add a few more days of admission.
• Children, starting from the age of ten, and adults, are prescribed a maximum of 1500 milligrams per day, despite the fact that it is necessary to drink the medicine three times.

The calculation of the exact dose is based on the weight of the child: usually 20 milligrams per kilogram of weight is taken into account. The resulting dosage is divided so that it is taken three times a day.

According to the indications, even pregnant women are allowed to take this medicine, but before that, the doctor must carefully consider whether taking the baby is too risky.

When the medication is used by female representatives during lactation, it is recommended to interrupt feeding. As mentioned above, the main substance of the antibiotic can be in breast milk, causing an allergy in the baby.

With the permission of the doctor, the drug is indicated even for pregnant women.

But if you decide to use Amoxicillin against sinusitis, remember that it also has certain contraindications:

• If a person is already sick with infectious monocleosis.
• In the presence of personal intolerance to the components of the drug, as well as allergies.
• For those who used to suffer (and now are ill) with bronchial asthma or urticaria.
• If colitis develops at the same time (the cause may be penicillins).
• When taking the drug is accompanied by severe side effects.

When observing side effects in adults and, especially, in children, you should consult a doctor - it is likely that he will change the dosage of Amoxicillin for sinusitis or replace this drug with some other antibiotic.

Here are some side effects that sometimes have to be faced by those who take the presented medicine:

• Associated with the work of the digestive tract - the stool worsens, the patient feels nausea, and sometimes even vomits, suffers from dyspepsia and dysbacteriosis.
• Allergic reactions - puffiness, skin rashes, runny nose and even the likelihood of anaphylactic shock.
• Associated with the nervous system - sleep problems, persistent anxiety, convulsions, migraines, and dizziness.
• Violations in the functioning of the circulatory system - the composition of the blood changes, which can lead to thrombocytopenia or anemia.
• Dysfunction of the renal system - in addition to hepatitis, it can be, for example, jaundice.
• Other effects are related to shortness of breath, the development of candidiasis, the appearance of joint pain.

But one should not think that one has to deal with side effects every time one takes the described medicine. This is more the exception than the rule.

Insomnia may be one of the side effects of this medication.

A few tips should be mentioned about the use of a drug such as Amoxicillin:

• It is best to take it with food as this minimizes the possibility of adverse reactions associated with gastrointestinal dysfunction.
• If someone has kidney problems, the doctor prescribing the antibiotic should know about it - it is likely that the interval between doses will be increased and the dose adjusted.
• Those who take estrogen-containing contraceptives at the same time as this remedy should be aware that the effectiveness of the drug against pregnancy will decrease.
• The possibility of superinfection cannot be ruled out, since the bacteria gradually adapt to the drug and become insensitive to it. If this happens, then antibiotic therapy requires correction.
• The drug does not affect the ability to drive.

It is worth considering that using only one antibacterial drug, one should not even hope to cope with inflammation of the maxillary sinuses. As a rule, only complex therapy helps, which involves the use of the following drugs in addition to the antibiotic:

• vasoconstrictors - most often these are special sprays and drops;
• antihistamines;
• immunomodulatory drugs that strengthen the immune system;
• mucolytics to help cough up;
• other symptomatic agents.

This significantly increases the likelihood of quickly coping with the inflammatory process in the maxillary sinuses and avoiding negative consequences.

It is advisable to take the medicine with food

Of course, sinusitis can be caused by a variety of reasons, and this must be taken into account when the doctor chooses the medicines that should be prescribed for treatment:

• Viral or bacterial infections can become the causative agent - in this case, antibiotic and antiviral drugs are likely to be prescribed.
• Damaged or deformed nasal septum from birth.
• The consequences of an allergy to some external irritant.
• Influence of harmful production, as a result of which chemical irritation is likely.
• The development of dental diseases, not cured in time.

Of course, Amoxicillin in adults and other antibiotics are not prescribed for every sinusitis. For example, in cases where the inflammation was caused by an allergy, taking such drugs is absolutely useless. With the viral nature of the disease, medications can be effective if a secondary bacterial infection has joined.

But in cases where it is definitely diagnosed that pathogenic bacteria are the causative agent of the disease, antibiotics are no longer enough.

Naturally, this tool is certified and, before being approved for mass use, many clinical trials have successfully passed. In addition, its benefits have been confirmed in practice - this is easy to verify by reading numerous reviews about how using this medicine, people were able to overcome different types of sinusitis.

Amoxil can be considered as an analogue of amoxicillin

The presented medication may have other trade names, such as:

• Gramox-D;
• Amoxil;
• Flemoxin Solutab.

The duration of action of the drug is about 9 hours, although after a couple of hours after taking it, it is concentrated in the blood in the maximum amount.

Digestibility does not depend on when the patient takes food - before, during or after the medication. However, it is recommended to consume it with meals.

Speaking about the main advantages of the described drug, it should be noted:

• high rates of its effectiveness;
• possibility of precise dosing;
• rapid absorption into the gastric and intestinal walls;
• minimum side effects;
• high degree of absorption;
• affordable cost.

But in no case do not self-medicate and do not prescribe doses of this drug to yourself. Naturally, it is necessary to get acquainted with the instructions for the use of Amoxicillin for sinusitis, but after the doctor prescribes this medicine. Moreover, this applies to the health of children, in whom inflammation of the maxillary sinuses develops much faster than in adults and can quickly lead to serious troubles, such as meningitis.

Of course, it is better to avoid taking antibiotics in the treatment of a particular disease. Everyone knows about it. However, if the bacterial nature of the disease has already been diagnosed, such drugs can no longer be dispensed with. Accordingly, their use is justified.

When using Amoxicillin, it is important to follow medical recommendations

You can not stop the healing process, not bringing it to the end. If you do this, you should not even hope for recovery, or you will have to face relapses and the need to prescribe very powerful drugs.

How many days to take Amoxicillin for sinusitis? This will be decided by a medical specialist, based on the current stage of the disease, the general condition of the patient, his individual characteristics, and so on.

But since it is better to prevent the disease than to fight it later, resorting to strong antibiotics, we recommend that everyone follow the preventive rules to avoid sinusitis.

First of all, do not delay the treatment of even the most common cold. Often we ignore the development of rhinitis, completely relying on the immune system, which supposedly should cope with a mild illness on its own. But this does not always happen: sometimes our body, for one reason or another, is unable to resist the disease, after which the inflammatory process begins and it comes to one of the sinusitis.

That's why it's so important to boost your immune system and take your treatment seriously, even if you're starting to get a runny nose.

Well, do not forget, of course, about the need for a healthy lifestyle, which, in addition to strengthening the immune system, involves proper sleep, rest, lack of emotional stress, proper nutrition, and so on.

A healthy lifestyle is the best prevention of sinusitis

Does Amoxicillin help with sinusitis? It has been proven in practice to help. However, it is better to do everything to avoid inflammation than to waste energy, time and nerves on its treatment.

Amoxicillin is a broad-spectrum antibacterial drug that is often prescribed for the treatment of diseases of the upper respiratory tract, in particular, sinusitis. Despite the fact that the pharmacological industry produces many new antibiotics, otolaryngologists often prescribe the time-tested Amoxicillin.

The antibacterial agent Amoxicillin belongs to the penicillins. The semi-synthetic antibiotic is effective against gram-positive and gram-negative bacteria, including those that cause the development of sinusitis: staphylococci and streptococci, as well as E. coli, Proteus, Haemophilus influenzae, Helicobacter pylori, certain strains of Klebsiella, Shigella and Salmonella. The drug has a bactericidal and antibacterial effect, that is, it is able to stop the growth and reproduction of bacteria and destroy them. Amoxicillin disrupts the synthesis of the main protein of the cell walls of microbes during their reproduction and causes the dissolution of microorganisms.

Amoxicillin has a detrimental effect on the pathogens of sinusitis, thereby eliminating the cause of the disease

The antibiotic is stable in an acidic environment, which is an advantage when taken orally, since gastric acid does not reduce its effectiveness. However, the drug is destroyed by penicillinase, an enzyme from the beta-lactamase group that some bacteria can produce, so Amoxicillin is often prescribed in combination with clavulanic acid, which suppresses the production of this enzyme. Amoxicillin with clavulanic acid - Augmentin, Amoxiclav, Flemoklav solutab, Liklav, Medoklav, Klamosar.

With sinusitis, an inflammatory process occurs in one or both of the maxillary sinuses. The main cause of the disease is pathogenic microorganisms that multiply in the paranasal sinuses and cause inflammation of the mucous membrane. Microbes can get there as a result of a runny nose, trauma to the mucous membrane, from foci of chronic infection - carious teeth, tonsils, etc. Pus accumulates in the sinuses, and if sinusitis is not treated, the consequences can be very serious.

Sinusitis is an inflammation of the mucous membrane of the maxillary sinuses and the accumulation of serous or purulent exudate in them.

Amoxicillin acts specifically on the infectious agent, this is the reason for its effectiveness in the treatment of maxillary sinusitis. When taken orally, the antibiotic is rapidly absorbed in the small intestine and accumulates in all tissues and body fluids, including the secretion of the maxillary sinuses. As part of complex therapy, Amoxicillin quickly eliminates the symptoms of sinusitis and completely cures the disease.

Amoxicillin quickly eliminates the symptoms of sinusitis, destroying microbial pathogens

Dosage forms

The drug is produced by various pharmaceutical companies in several forms:

• coated tablets;
• capsules;
• granules for suspension preparation.

Suspension for injection is used only in veterinary practice, for the treatment of animals.

The active substance of any form of release is amoxicillin trihydrate (at a dosage of 250 mg, 500 mg or 1 g).

Additional components of tablets:

• microcellulose;
• polyvidone;
• magnesium stearate;
• starch;
• tablet shell:
  • talc;
  • titanium dioxide;
  • hypermellosis.

Amoxicillin tablets are prescribed for adult patients

• microcellulose;
• magnesium stearate;
• capsule shell:
  • gelatin;
  • titanium dioxide;
  • food colorings.

Amoxicillin capsules are easy and convenient to take

Suspension granules contain substances:

• sucrose;
• citrate, saccharinate, sodium benzoate;
• guar gum;
• simethicone;
• natural flavors.

Amoxicillin in granules for the preparation of a suspension is prescribed for children

Side effects of the drug and contraindications to the appointment

The tool has many contraindications and limitations. Amoxicillin is not prescribed if the patient:

• individual intolerance to antibiotics of the penicillin group;
• Infectious mononucleosis;
• allergic diseases, including diathesis, hay fever or bronchial asthma;
• severe renal or hepatic failure,
• malignant blood diseases;
• intestinal pathology:
  • severe dysbacteriosis;
  • colitis;
  • enteritis.

The use of an antibiotic during the period of bearing a child is allowed if the benefit to the mother's body significantly outweighs the possible risk to the fetus. In this case, the pregnant woman should undergo a course of treatment with Amoxicillin under strict medical supervision.
Since the drug easily passes into breast milk, the antibiotic is not used during lactation. If, nevertheless, the drug is prescribed to a nursing mother, then it is recommended not to breastfeed the child for the duration of treatment.

For children, the drug can only be prescribed by a pediatrician or a pediatric ENT in an individual dosage.

Amoxicillin is not prescribed simultaneously with such drugs:

• bacteriostatic antibiotics and sulfonamides;
• oral contraceptives (their effectiveness decreases);
• antacids, laxatives, aminoglycosides (reduce the absorption of the antibiotic).

Almost every drug has side effects. Amoxicillin can cause the following reactions:

• nervous system:
  • headaches;
  • dizziness;
  • sleep disorders;
  • nervous excitability;
  • rarely - convulsions and disorders of consciousness;
• digestive organs:
  • loss of appetite;
  • nausea;
  • vomit;
  • diarrhea;
  • stomatitis;
  • glossitis;
• heart and blood vessels:
  • tachycardia;
• allergic reactions:
  • hives;
  • exfoliative dermatitis;
  • various skin rashes;
  • anaphylactic shock;
  • angioedema;
  • inflammation of the nasal mucosa, eyes.

Anaphylactic shock is the most dangerous condition that can be caused by taking Amoxicillin.

In addition, you may experience:

• joint pain;
• difficulty breathing;
• change in the blood formula;
• nephritis;
• dysbacteriosis;
• thrush;
• hemorrhagic colitis;
• superinfection.

Any of these manifestations is a signal to cancel the drug.

Sinusitis is a disease far from harmless, therefore it is impossible to be treated on your own, without prior consultation with an otolaryngologist.

In case of inflammation of the paranasal sinuses, a swab is necessarily taken, followed by bacterial culture to determine the pathogen and sensitivity to antibiotics. Only according to the results of the examination, a competent otolaryngologist will prescribe appropriate antibiotic therapy.

The dosage of the antibiotic is determined by the doctor. You can drink Amoxicillin regardless of food intake, since food does not affect its absorption. However, it is recommended to take the tablets or capsules after a meal in order to reduce the undesirable effect on the digestive tract. Usually, the daily dose of the antibiotic is administered in two doses, with an interval of 12 hours, or in three doses with an interval of 8 hours. The course of treatment for sinusitis averages 7-12 days, the duration of therapy depends on the patient's condition and is adjusted by the doctor.
Tablets and capsules are taken whole, without chewing or breaking, washed down with water.

Alcoholic beverages should not be consumed during antibiotic treatment.

Children under 10 years of age are prescribed an antibiotic in the form of a suspension. Until the age of two, the daily dose is calculated depending on the body weight of the baby.

On the pharmacy shelves you can find many drugs with Amoxicillin. Especially popular are combined products with clavulanic acid. An otolaryngologist may prescribe antibiotic analogues: Flemoxin Solutab, Osmamox, Amosin, Gramox, Hikoncil, Ecobol, Amofast, Augmentin and others. All these funds are developed on the basis of Amoxicillin.

If the patient does not tolerate penicillin antibiotics or they are ineffective, the doctor may prescribe an antibacterial drug with another active substance.

13853 09/11/2019 5 min.

Inflammation of the maxillary sinuses is a condition characteristic of any viral rhinitis. Why, then, at the word "sinusitis" many of us immediately panic? Because under this diagnosis, an already neglected, chronic form of the disease is often hidden, requiring a long and difficult treatment. To avoid it, at the very beginning of the acute manifestation of the disease, the doctor prescribes antibiotics for sinusitis, for example, Amoxicillin, which will help to avoid the puncture so frightening for all patients (puncture of the sinuses in order to wash them).

Why use Amoxicillin and how it helps

Not every form of sinusitis requires the use of antibiotic therapy - it is absolutely useless in case of allergic and viral etymology of the disease, the antibiotic will not help those who have an occupational disease. But in the case of a bacterial lesion, an antibiotic cannot be dispensed with - it will help prevent the prolongation of the disease and the adoption of a chronic form.

What antibiotics to take for sinusitis read.

One of the best drugs often prescribed by otolaryngologists for the treatment of sinusitis is Amoxicillin, and in this article we will consider the advantages and disadvantages of this medicine. Amoxicillin for sinusitis is a very effective and useful remedy.

Find out if Amoxicillin helps with a cold.

The action of the drug

Amoxicillin is a semi-synthetic antibiotic of the penicillin group with a powerful effect: it neutralizes gram-positive and gram-negative microorganisms, including such dangerous ones as E. coli, salmonella, shigella, as well as streptococcus and staphylococcus. This is a time-tested, certified medicine that has strong bactericidal properties and helps to cope with the disease no worse than newfangled expensive analogues.

The drug is an almost universal antibiotic, the dosages of which are designed for adults, children, as well as debilitated elderly people and bedridden patients.

What does the temperature mean for sinusitis?

The drug is available in the form of capsules (0.25 and 0.5 g), tablets (1.0 g), suspension (5 ml - 0.125 g), solution for per os - by mouth (1 ml - 0.1 g) , powder for the preparation of droppers and intramuscular (1 g, diluted with saline).

The medicine has many trade names:

• Flemoxin Solutab;
• Augmentin;
• Amoxil;
• Amoxicillin trihydrate;
• Gramox-D.

The undoubted advantage of Amoxicillin is that its digestibility does not depend on food intake in any way - the patient does not have to reshape his usual regimen.

Among the advantages of the drug can be noted:

• high efficiency;
• the ability to accurately calculate the dose in accordance with the individual requirements of the patient;
• the ability to be absorbed into the walls of the stomach and intestines, which is not characteristic of every antibacterial agent;
• safety and many years of experience in the use, including in the treatment of newborns;
• penetration into all organs except the brain and spinal cord;
• fast and high (up to 93%) absorption rate;
• affordable price.

Read also about how to do it right.

Dosage for children

Treatment of sinusitis with Amoxicillin should take place as prescribed and under the strict supervision of a doctor who will set the child an individual dose of antibiotic depending on his weight and age category, and he will definitely tell you how to take it and whether the drug helps or not.

The antibiotic takes effect very quickly - within 15-20 minutes after ingestion, and is active for 7-9 hours.

Average dosages:

1. For children from birth to 2 years, a single dose is calculated as follows: 20 mg of the drug is multiplied by 1 kg of body weight per day and divided into three doses.
2. Children from 2 to 5 years old are recommended to take an antibiotic in the form of a suspension, which manufacturers often give a pleasant taste, focusing specifically on this age group. A single dose for such children is 125 mg (half a scoop) three times a day.
3. In the case of children from 5 to 10 years old, the dosage is doubled - its one-time rate is 250 ml three times a day.

You will also be interested to know how the .

Self-medication often ends with an overdose of the drug with all the attendant troubles, since when determining a single dose, the weight of the child is much more important than his age. This is especially true for weak and premature babies.

Dosage for adults

For patients over the age of 10 years (weighing more than 40 kg) and adults in the absence of pathologies, the use of Amoxicillin is indicated in accordance with the instructions for the drug. The maximum allowable daily dose of the suspension in this case is 6 g. For moderately severe infections, 500 ml of syrup is prescribed 3 times a day, with complex forms of sinusitis, it is possible to increase the dose to 0.75-1 g three times a day intramuscularly.

Can pregnant women take amoxicillin

Pregnancy is a special condition in which everything that a woman ingests enters the body of her baby. This dependence makes expectant mothers have a negative attitude towards taking antibiotics, and this is absolutely correct. But there are situations in which you have to choose the lesser of two evils - in particular, pregnant women should be aware that intrauterine infection of the fetus with a bacterial infection can cause such serious consequences as pneumonia, developmental disorders incompatible with life, and severe organic lesions of the central nervous system. In this case, the use of Amoxicillin is justified and necessary.

How to treat signs of sinusitis in adults will help to understand.

The dosage is determined by the doctor. In order to protect herself and the child as much as possible, a woman should carry out treatment under his strict supervision, and seek advice in case of any warning signs.

Contraindications to the treatment of sinusitis with Amoxicillin

Like any medication, Amoxicillin has a number of contraindications and side effects. Taking the medicine is unacceptable in the following cases:

• individual sensitivity to its components;
• liver failure;
• diathesis;
• bronchial asthma;
• some diseases of the gastrointestinal tract;
• infectious mononucleosis;
• oncological diseases of the blood.

Treatment should be stopped immediately for those patients who experience the following side effects:

• indigestion: vomiting, diarrhea, constipation for many days;
• allergic reactions: rash, shortness of breath, anaphylactic shock;
• increased manifestations of sinusitis (increase in the amount of mucus, constant headache, etc.);
• inflammation of the membranes of the eyeballs (conjunctivitis).

Despite the fact that this antibiotic rarely manifests itself from the negative side, patients should be very attentive to the reaction of their body and notify the attending physician of any side effects.

What antibiotics to take for sinusitis is indicated.

Video

This video will tell you how to properly take the antibiotic Amoxicillin for sinusitis.

Bacterial sinusitis is a disease that responds well to treatment with Amoxicillin if the patient completes the course of treatment (usually 5-7 days). If treatment is interrupted prematurely, the disease may recur, and then the doctor will be forced to prescribe an even stronger medicine to eliminate it. According to reviews, the effectiveness of the drug is beyond doubt. You will find a list of drops in the nose with an antibiotic for sinusitis.