When is the best time to take folic acid? Folic acid when planning a pregnancy: a small pill for a big event

Not all vitamin complexes are exceptionally useful. Many drugs can lead to an overabundance of certain substances. Therefore, before using medications, you need to consult a doctor for advice.

In recent years, the benefits and harms of its use will be presented in the article. You will also learn how to use it. Separately, it is necessary to mention the opinion of doctors about this remedy.

General description of the drug: composition

The drug "Folic acid" contains several components. It contains vitamin B9. Also, the manufacturer can add additional components that usually do not have a significant effect on the human body.

The cost of the drug depends on the production and number of tablets. The dosage also matters, because one tablet can contain 400, 800 or 1000 micrograms of the active substance. The average cost of the drug is in the range of up to one hundred rubles.

benefit and harm

The positive and negative effects of this substance are still being debated. A few decades ago, the decision was made to fortify foods with water-soluble folate.

Folic acid plays an important role in the human body. It is involved in the metabolism of amino acids, the synthesis of nucleic acids. This component is indispensable in the formation of new cells, hematopoiesis. Folic acid contributes to the normalization. Also, the substance is necessary for the immune and cardiac systems.

The benefits and harms of folic acid have been compared by scientists. Professors came to the conclusion that almost never can harm. However, its overabundance still entails unpleasant consequences. Among them are problems such as the formation of kidney stones, tumors in the mammary glands, and so on.

Indications for use

In what cases is it necessary to take tablets with the trade name "Folic acid"? Benefits and harms to the patient must be pre-evaluated by the doctor. Therefore, in order not to experience unpleasant reactions or get an excess of the active ingredient, it is necessary to consult a doctor. The instructions indicate that vitamin B9 is prescribed for its deficiency in the body. It can manifest itself with the following symptoms:

• megaloblastic anemia;
• leukopenia;
• chronic gastroenteritis;
• intestinal tuberculosis;
• restlessness and constant feeling of fear;
• digestive problems;
• or hair loss and so on.

For women

Quite often, doctors prescribe drugs such as folic acid during pregnancy. The benefits and harms for women from its use are also controversial. Vitamin B9 is essential for the normal development of the embryo. Without its use, the likelihood of developing neural tube defects is high. Also, the drug has a positive effect on the formation of the whole organism. It is important to take enough folic acid for the proper development of the fetal brain.

What then is the harm of the substance? The thing is that an excess of vitamin B9 negatively affects diseases of the mammary glands. If a woman has a tumor in this place, then her condition can worsen greatly.

Contraindications to the use of the drug and adverse reactions

What are the benefits and harms for a person from the drug "Folic acid", you already know. If you take the medication as prescribed by a specialist in accordance with the indicated dosages, then you will receive an exclusively positive effect. Vitamin B9 is never prescribed to patients with hypersensitivity to it. It is also worth paying attention to additional components, which may differ from individual manufacturers.

Among the adverse reactions, the instruction indicates an allergy. It can be mild or severe: swelling, rash, itchy skin, and so on. There is evidence that the use of the drug in some people caused a fever. If you have unpleasant manifestations after the start of therapy, then you should definitely consult a doctor.

How to use

Before using the medication, be sure to read the annotation. Read the information about the benefits and harms of Folic Acid tablets. For men and non-pregnant women, the drug is prescribed at a dose of 400 mcg. During the period of bearing a child, the need for folic acid increases. Expectant mothers are advised to consume up to six hundred micrograms of folate.

For children, the medication is prescribed in a lower dosage. It all depends on the age and body weight of the child. The duration of therapy is also determined individually. Tablets should be taken orally with water. If possible, take the medication during meals.

What do the doctors say?

Gynecologists say that the benefit is achieved by taking the drug "Folic Acid", and they cannot be harmed during pregnancy. Doctors explain their statement as follows. During the bearing of a child, a woman's diet changes. Often, expectant mothers are disgusted with food that contains vitamin B9. These are meat, mushrooms, root crops, greens. In this case, there is a lack of folic acid in the body. Everything is aggravated by the fact that the fetus needs this vitamin daily. Therefore, often pregnant women are prescribed the drug without additional examinations.

Elderly people need folic acid to maintain the functioning of the heart and blood vessels. Tablets are prescribed in courses with a break. For children, medication is prescribed much less frequently. There must be good reasons for this. Most children get the right amount of folic acid from food.

Summing up

You have learned a lot about folic acid. The harm or benefit to be gained from therapy depends on the situation and the condition of the patient. If there is an excess of vitamin B9 in the body, then taking it can be dangerous. However, this situation occurs very rarely. Most patients are deficient in folic acid. Therefore, it is advisable to use it in the doses described above.

You can buy folic acid without a prescription at any pharmacy. If at the same time you are taking vitamin complexes, then pay attention to whether the described component is there so as not to provoke its overabundance in the body. Good health and good health to you!

Thanks

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

general information

About the benefits folic acid(vitamin B 9) people have known for a long time, but only in the last 10 years, doctors have begun to actively promote preventive courses of folic acid intake for pregnant women and those suffering from iron deficiency anemia.

Folic acid is involved in metabolism, in the production of DNA, plays an important role in the synthesis of immune blood cells, and normalizes the function of the digestive tract. For pregnant women, folic acid is essential because it plays an important role in the development of the neural tube of the fetus. With a normal level of vitamin B 9, the likelihood of malformations in the fetus is significantly reduced. In addition, it is necessary for the normal growth and development of the placenta.

Discovery history

In 1926, microbiologist V. Efremov discovered a specific form of anemia in pregnant women - megaloblastic anemia. Then vitaminology developed rapidly, many scientists conducted research in this area of ​​knowledge. Most attention was paid to the nutritional factor. Efremov accurately determined the presence of a certain anti-anemic factor in the liver tissue - significant improvements were observed in patients who received food from the liver.

In 1932, the British physician Wils, who worked for many years in India, found that some pregnant women suffering from megaloblastic anemia did not improve when using a purified extract of liver cells. However, these women recovered completely after consuming the crude extract. From this, Wills deduced that some important factor causing recovery was destroyed during the cleansing. This substance was soon isolated and named the Wills factor. Later it was called vitamin M. In 1941, it was found that spinach and parsley leaves are rich in this substance - therefore it was renamed folic acid (translated from Latin folium - leaf).

Mechanism of action

Once in the body, vitamin B 9 is converted into tetrahydrofolate, which serves as a component of many enzymes, and also participates in a number of biochemical reactions, such as protein metabolism. As a result, the body synthesizes amino acids necessary for the formation of proteins, epinephrine and some other factors. Also, vitamin B 9 has an effect similar to estrogens - it determines the correct development of the woman's reproductive system.

It is well known that the first and most important step in the division of any cell is the division of the DNA molecule. It is in the process of DNA replication that vitamin B 9 takes an active part. In addition, it plays an important role in the synthesis of RNA, amino acids, and improves the absorption of iron. Therefore, the lack of folic acid is primarily dangerous for rapidly dividing cells.

Mood also depends on the level of folic acid. It is involved in the metabolism of neurotransmitters such as serotonin and adrenaline, which have a significant impact on the functioning of the nervous system.

Folic acid stimulates appetite and is involved in the release of hydrochloric acid in the stomach.

Need for folic acid

The human liver usually contains some folacin, which can prevent hypovitaminosis for 3-6 months. The body of an adult needs 0.4 mg of folic acid per day, during pregnancy and lactation - 0.4-0.6 mg, a child of the 1st year of life - 0.04-0.06 mg. In the normal state of the intestinal flora, vitamin B 9 can be produced endogenously.

Folic acid and pregnancy

Daily maintenance of normal folic acid levels in the months before pregnancy helps to reduce the risk of congenital malformations of the fetus. Clinical studies have shown that 80% of cases of malformation can be prevented if a woman begins to compensate for the lack of vitamin B 9 before pregnancy.

In the Russian Federation, it is generally accepted that the need for pregnant women without symptoms of deficiency of this micronutrient is 0.4 mg per day. During breastfeeding, the need is 0.6 mg per day.

During pregnancy, a woman's body consumes much more folic acid than before pregnancy. Vitamin B 9 is not stored in reserve, so it is important to get it daily from external sources. It is very important to maintain the required level of folic acid in the first trimester, when the fetal nervous system develops.

The most important role of vitamin B 9 for the fetus is the development of the neural tube. She also takes part in the renewal and mitosis of the cells of the mother's body, in particular the cells of the internal organs, which must be constantly updated.

Already in the second week of pregnancy, the brain begins to actively develop in the embryo. It was at this time that even a short deficiency of vitamin B 9 threatens with serious, often irreparable consequences. Since this micronutrient is necessary in the process of mitosis, which is extremely important for rapidly dividing and developing cells (these primarily include neurons and other cells of the nervous tissue), its deficiency primarily affects the developing nervous system.

Folic acid is involved in the production of the main blood cells (erythrocytes, leukocytes and platelets), which is important for both the mother and the fetus.

For the normal course of pregnancy, maintaining the health of the woman and the fetus, doctors recommend starting taking folic acid in the form of tablets 2-3 months before the planned pregnancy, and continuing until childbirth. When using vitamin B 9, you must adhere to the doses recommended by your doctor, since an excess of this micronutrient is just as dangerous as its deficiency.

Vitamin B 9 is the only micronutrient whose role during pregnancy is not underestimated even by opponents of synthetic vitamin preparations and medicines in general. Therefore, even if you avoid any medications during pregnancy, do not refuse a course of vitamin B 9, at least for prevention purposes - this will save you and your child from a number of unjustified risks. Although sometimes it is necessary to compare the dosage prescribed by the doctor with the body's needs for folic acid.

Folic acid deficiency and its consequences

During heat treatment of food, up to 90% of vitamin B 9, which is part of raw foods, can be lost. For example, when frying meat, up to 95% of vitamin B 9 is destroyed, when cooking meat and vegetable products - from 70 to 90%, when boiling eggs - about half.

Vitamin B 9 deficiency can develop due to its low content in the diet, impaired absorption of micronutrients in the intestine, or with an increase in the need for this substance (pregnancy, lactation).

A common cause of this hypovitaminosis is the regular use of alcoholic beverages.

Folic acid deficiency is the most common symptom in pregnant women and infants. Vitamin B 9 deficiency in the fetus develops as a result of its lack in the mother's body, and in infants - due to its insufficient content in breast milk.

Folic acid deficiency in the body of a pregnant woman can serve as a factor in the whole a number of serious violations:

• miscarriage;
• congenital malformations;
• mental retardation;
• malformation of the neural tube;
• spina bifida (in the fetus);
• malformations of the circulatory system;
• cleft lip or cleft palate;
• anemia.

Symptoms of vitamin B 9 deficiency may take 8-30 days to appear, depending on the diet. The first symptoms of this hypovitaminosis are a breakdown, nervousness and poor appetite. We should not forget about replenishing the deficiency of vitamin B 9 during breastfeeding, since the body maintains the required level of this vitamin in milk, even to the detriment of itself. Therefore, with a lack of folic acid in the diet of a nursing mother, the above symptoms often occur, which increase postpartum depression.

Lack of vitamin B 9 is not always accompanied by obvious symptoms. At the same time, according to research results, a lack of folic acid is present in 20-100% of people, depending on where they live. This is one of the most common hypovitaminosis. However, even in the absence of certain clinical symptoms, the likelihood of heart attack and stroke increases significantly, immunity decreases.

Folic acid deficiency often leads to the development of pernicious anemia in premature babies. An increase in the need for vitamin B 9 occurs in a number of pathologies: leukemia, hemolytic anemia, chronic infectious diseases, carcinomatosis.

First of all, with a lack of vitamin B 9, megaloblastic anemia develops. With this type of anemia, not only does the content of erythrocytes in the blood fall, but their activity is also disrupted, since most of them do not mature in the bone marrow. If at the same time you do not make up for the lack of folic acid, symptoms such as loss of appetite, nervousness, loss of strength develop. Later, vomiting, diarrhea, alopecia join. Possible morphological disorders of the skin, the appearance of ulcers in the oral cavity and pharynx. If not treated promptly, megaloblastic anemia can lead to death.

In recent years, a number of clinical trials have been carried out, as a result of which it was found that vitamin B 9 deficiency, disrupting the metabolism of sulfur amino acids, leads to a delay in the blood of the amino acid homocysteine. Homocysteine ​​has a negative effect on the intima of blood vessels, which leads to the appearance of atherosclerotic plaques and increases the risk of heart attacks and strokes.

Violation of the absorption of vitamin B 9 can occur with diseases of the stomach, gastrectomy, when the body is deficient in anti-anemic factors (Castle factors) synthesized in the stomach. Folic acid can enter the bloodstream only by combining with antianemic factors, respectively, when they are deficient, the level of folic acid in the blood drops.

In addition to folic acid, the Castle factor carries cyanocobalamin into the blood. Therefore, prolonged use of vitamin B 9 preparations in an increased dosage can lead to a lack of cyanocobalamin.

Also, a lack of vitamin B 9 is observed in severe liver pathologies. It is in the liver that the vitamin is transformed into tetrahydrofolate, which takes part in biochemical reactions. Folic acid in its primary form is useless for the body.

If the body is deficient in vitamin B 9, the hematopoiesis system may be disrupted: red blood cells do not mature, and defective cells that are not able to transport oxygen are released into the blood. This is one of the reasons for the malformation of the nervous system in the fetus, since neurons cannot fully grow and develop under conditions of hypoxia.

Together with erythrocytes, the synthesis of leukocytes and platelets is disrupted, which can provoke a decrease in immunity and disrupt blood clotting. In pregnant women, vitamin B 9 deficiency may be accompanied by an iron deficiency. This increases the risk for both mother and baby.

Vitamin B 9 deficiency can develop with a lack of vitamins in the diet, fasting, following unbalanced diets for weight loss. However, the most common vitamin B 9 deficiency factor is dysbacteriosis. Dysbacteriosis develops as a result of prolonged, often uncontrolled intake of antibiotic drugs, incl. without a prescription from a doctor.

In the United States, there is a law requiring manufacturers to add a certain amount of vitamin B 9 to flour in order to prevent consumers from becoming deficient in this substance. In the USA, the prophylactic dose of vitamin B 9 is twice as high as in the Russian Federation.

Foods containing folic acid

Vitamin B 9 is part of all tissues of humans, animals, plants and microorganisms. The human body is unable to produce folic acid. Therefore, it is obtained from food, or is produced by the microflora of the colon. Therefore, in violation of the functions of the intestine or dysbacteriosis, the production of vitamin B 9 may be insufficient. In such situations, an additional source of this micronutrient is needed.

Vitamin B 9 is found in large quantities in plant foods: spinach, onions, dill, parsley, beans, peas, buckwheat, oats, bran, bananas, walnuts, grapefruit, dried apricots, melons, yeast, pumpkin, mushrooms, beets, turnips and others

Also, a source of folic acid is meat and animal products: beef, lamb, pork, liver, kidneys, poultry meat, milk, eggs, trout, perch, cheese, etc.

A plate of cereal porridge with milk and a glass of orange juice fill 50% of the body's daily requirement for vitamin B 9 .

The use of bifidobacteria stimulates the endogenous formation of folic acid in the intestine.

Vitamin B 9 decomposes quite quickly under the influence of sunlight and simply during prolonged storage of food, as well as during thermal processing of products. The most rapidly destroyed folic acid contained in plant foods. Folic acid in meat is more stable.

Therefore, in order to preserve the vitamin in foods, it is recommended to consume raw foods. Vegetables are best consumed in the form of raw salads. In such a salad, it is best to add garden cabbage, parsley, dill, beet, mint or dandelion leaves. It is also useful to add young nettles to the salad. Of the juices, it is better to drink orange and tomato - they contain the most folic acid.

Among meat products, the most folic acid is found in the liver. The liver can be lightly fried and boiled for a short time - while vitamin B 9, which is part of it, is not destroyed.

Medicines containing folic acid

folic acid tablets- the most convenient dosage form for dosing (one tablet contains 1 mg of the substance). In addition, today it is the most economical option. To fully compensate for the deficiency of a pregnant woman in vitamin B 9, it is enough to take 1 tablet per day. However, given the prevalence of folic acid deficiency, which may not manifest itself externally, 2-3 tablets per day can be taken 2-3 months before pregnancy and in the first trimester. This dosage is recommended by doctors, since an overdose from such an amount of the drug is impossible, and the consequences of a lack of folic acid are extremely dangerous. In this situation, doctors resort to justified reinsurance.

Folic acid is available as a drug Folacin. One tablet of the drug contains 5 mg of vitamin B 9. This is much more than the daily allowance, even for a pregnant woman. Excess folic acid has neither positive nor negative effects, but is simply excreted from the body. 1 tablet Apo Folica also contains 5 mg of vitamin B 9 . Given the increased content of the substance in the tablet, Folacin and Apo-Folic are used only for acute and severe vitamin deficiency. In order to prevent these drugs are not recommended.

In one tablet of the drug Folio contains 0.4 mg of vitamin B 9 and 0.2 mg of iodine. The advantage of this dosage form is that it contains two micronutrients, so there is no need for additional use of iodine preparations. The dose of vitamin B 9 in one tablet is low, so it is recommended as a prophylactic drug. Folio is not prescribed for acute deficiency or increased need for folic acid.

Vitamin B 9 is part of multivitamin preparations for pregnant women. The content of folic acid in one tablet each drug is different:

• Materna - 1 mg;
• Elevit - 1 mg;
• Vitrum prenatal - 0.8 mg
• Vitrum prenatal forte - 0.8 mg
• Multi-tabs perinatal - 0.4 mg
• Pregnavit - 0.75 mg.

All complexes contain a prophylactic dose, so the dosage of vitamin B 9 should be calculated taking into account its content in the vitamin complex. With a normal level of folic acid in the body, there is no need for its preparations if a pregnant woman is already taking any multivitamin complexes.

Vitamin B 9 is absorbed much better from drugs than from food.

In addition to pharmaceuticals, folic acid can be obtained from dietary supplements.

Indications

Folic acid is indicated for the following conditions:

• folate deficiency anemia;
• anemia as a complication after gastrectomy;
• sprue (tropical diarrhea);
• chronic inflammation of the intestine;
• intestinal tuberculosis;
• pregnancy;
• lactation period;
• vitamin B deficiency 9.

Taking the drug in therapeutic doses (exceeding the daily requirement) is indicated in two cases:

• if there are pronounced signs of folic acid deficiency (in this case, the dosage is calculated individually by the attending physician);
• if there are factors that increase the need for vitamin B 9, or stimulate its excretion from the body.

Cases in which it is necessary to take therapeutic doses of the drug:

• use of combined oral contraceptives before conception;
• the use of Maalox or Phosphalugel;
• taking anticonvulsants during the planning period and during pregnancy;
• protein diet before conception;
• lack of plant foods in the diet;
• disruption of the digestive tract;
• vomiting during pregnancy.

Folic acid is used in the treatment of tropical diarrhea (spru). Sprue is a progressive inflammation of the small intestine, accompanied by diarrhea, impaired intestinal absorption, dystrophic condition, symptoms of megaloblastic anemia, dysfunction of the endocrine glands, and progressive calcium deficiency. The main factors causing tropical diarrhea: infection, beriberi, protein deficiency in the diet with an excess of saccharides. With this pathology, vitamin B 9 is taken at 5 mg per day in order to normalize the process of erythrocyte synthesis.

Clinical trials have demonstrated that vitamin B 9 may have a positive effect in the prevention of Alzheimer's disease. In persons with this pathology, as a rule, the content of folic acid and cyanocobalamin in the blood is reduced.

Dosage and administration

If a woman has any of the above factors, then during pregnancy planning and in the first trimester, it is necessary to consume 2-3 mg of vitamin B 9 per day. Also, taking the drug in an increased dosage is necessary with a high probability of a violation of the development of the neural tube. Such a risk is present in women with epilepsy, diabetes, as well as in the presence of similar disorders in relatives in a direct line.

The need for folic acid during pregnancy is 0.4 - 0.8 mg per day. However, in a deficient state, the dosage is significantly increased in order to compensate for the lack of a vitamin. The neural tube of the embryo begins to develop at 3-5 weeks of gestation. At this time, a woman may not know about pregnancy, and may not complete a timely course to compensate for folic acid deficiency. Therefore, vitamin B 9 must be taken 1-3 months before the expected pregnancy. It is most important to maintain the required level of folic acid in the first trimester.

Folic acid must be taken during lactation in the amount of 0.3 mg per day (possible in the form of a multivitamin complex). This serves as a preventive course for both mother and child. If you use the drug in high doses (for example, 1 mg), then the excess amount of the vitamin is simply excreted from the woman's body without harming either her or the baby.

It is important to observe the regularity in the use of vitamin B 9. However, given that any drug contains a dose that exceeds the daily requirement for a vitamin, skipping one dose should not cause concern.

• Atherosclerosis. 5 mg of vitamin B 9 per day for two weeks, then - 1 mg. It is recommended to use in the form of a B-group vitamin complex.
• Aphthous stomatitis. As a rule, aphthae (sores on the oral mucosa) appear along with cracks in the lips with a deficiency of vitamins and micronutrients involved in hematopoiesis. Among them: vitamin B 9, iron and cyanocobalamin. The recommended dosage is 5 mg of vitamin B 9 3 times a day and 10 mg of iron glycinate for 120-180 days. Once every 30 days, inject cyanocobalamin - 1 mg. During treatment, it is necessary to regularly check the level of cyanocobalamin.
• Viral hepatitis. Folic acid is used as an aid. It is recommended to take 5 mg 3 times a day for 10 days, then 5 mg once a day.
• Gingivitis and periodontitis. Take orally 1 mg of vitamin B 9 times a day, rinse the mouth 2 times a day for one minute with a 1% solution of the vitamin for 60-70 days.
• Depression. Often seen in individuals with folic acid deficiency. Take 2-5 mg every day in combination with B-group vitamins.
• Osteochondrosis. Vitamin B 9 is involved in the formation of a framework from collagen, on which calcium salts accumulate. Without a collagen framework, the bone does not acquire the necessary strength. The recommended dosage is once a day, 5 mg of vitamin B 9, 50 mg of vitamin B6, 50 mg of B-complex vitamins.
• Tumor of the large intestine. If any of your relatives in a straight line had this oncological disease, it is strongly recommended to take 1-5 mg of vitamin B 9 and 100 mg of B-complex vitamins once a day.
• Spasm of the colon. It manifests itself in the form of alternating constipation and diarrhea, colic and bloating. Lack of vitamin B 9 can lead to chronic constipation, which leads to spasm of the colon. It is necessary to start with 10 mg of the vitamin once a day. If no progress is observed after 15-20 days, the dose should be increased to 20-60 mg per day until a positive effect occurs. Further, the dosage is gradually reduced. At the same time, it is recommended to take 0.1 g of B-complex vitamins once a day. During the course, it is necessary to regularly check the level of cyanocobalamin. It is recommended to include oat bran in the diet, which contains water-soluble fiber. Wheat bran is not suitable in this case, since their fiber is insoluble.
• Epilepsy. After an epileptic attack, the level of vitamin B 9 in the brain decreases. Anticonvulsants also reduce its plasma concentration. As a result, seizures become more frequent. Usually, epilepsy is prescribed 5 mg once a day. However, the drug should be taken only after consulting a doctor.

Overdose

Overdose happens very rarely. To do this, the body must receive hundreds of times more than the required amount of folic acid (20-30 mg). With a slight excess of the required amount of the drug, the excess folic acid is excreted without causing any harm to the body. However, like any medication, vitamin B 9 preparations can cause allergies.

A serious disadvantage of long-term use of vitamin B 9 preparations is that it hides the symptoms of megaloblastic anemia, but does not stop the neurological disorders characteristic of this disease. Therefore, with prolonged use of vitamin B 9 preparations, a latent progression of severe neurological disorders due to a lack of cyanocobalamin is possible. Just 10 years ago, it was generally accepted that there was no overdose of this micronutrient. However, studies are now known that indicate that pregnant women who have been taking high-dose vitamin B 9 preparations for a long time give birth to children with weak immunity, a tendency to bronchial asthma and colds.

Hypervitaminosis

High doses of vitamin B 9 can cause dyspepsia or irritability in a child. Prolonged use of the vitamin at an increased dosage is not recommended, as this can lead to a drop in the blood content of cyanocobalamin.

Side effects

Depending on individual tolerance, folic acid preparations can cause allergic manifestations, bronchospasm, skin redness, hyperthermia, rash.

Vitamin B 9 does not have a toxic effect on the human body. Clinical studies have been conducted on the long-term use of vitamin B 9 at a dosage of 15 mg per day (40 times the daily requirement of the body). According to the results of studies, the drug did not have any toxic effect. However, prolonged intake (more than 90 days) of vitamin B 9 at an increased dosage can lead to a drop in the level of cyanocobalamin in the blood, which can cause anemia. Increased doses of the vitamin can provoke disorders of the digestive tract, increase excitability, and cause an imbalance in the functioning of the kidneys.

Some drugs reduce the content of vitamin B 9 in blood plasma. Among them:

• acetylsalicylic acid (at an increased dosage);
• nitrofurans (taken for urinary tract infections);
• combined oral contraceptives;

Folic acid and men's health

Vitamin B 9 is necessary for both women and men. With chronic vitamin deficiency, men can develop a number of pathologies, including infertility and megaloblastic anemia. Taking folic acid in a therapeutic dosage eliminates such complications.

The main indicator of men's health is considered to be the state of spermatozoa. Spermatozoa are the same cells, their synthesis requires protein and nucleic acids. In the absence of vitamin B 9, sperm synthesis is impaired. With a lack of a vitamin, the concentration of spermatozoa decreases, and their condition worsens: spermatozoa may have an unnatural shape or not have a tail, which reduces their mobility. But the worst thing is that such spermatozoa may have the wrong number of chromosomes, and this is the main factor in hereditary diseases in children (eg Down's syndrome).

Vitamin B 9 and the hormone testosterone determine the normal development of spermatozoa. Folic acid is extremely important for men in puberty, since it is one of the factors in the development of secondary sexual characteristics (coarsening of the voice, facial and body hair, intensive growth).

Folic acid in the treatment and prevention of cancer

Vitamin B 9 prevents cancer. But if the disease has already begun, then the drug should not be used, since folic acid will promote the division of cancer cells. In such situations, drugs are used that inhibit the activity of vitamin B 9, such as methotrexate. This slows down the growth of the tumor. In order to prevent metabolic disorders, a drug is prescribed that replaces vitamin B 9 - folinic acid. Given the higher risk of cancer in older people, they are advised not to take folic acid supplements without a doctor's recommendation.

Leucovorin is a folinic acid-based drug successfully used as part of cancer chemotherapy. It reduces the severity of intoxication after the use of cytotoxic drugs (vomiting, diarrhea, hyperthermia, bone marrow damage).

Recent studies by scientists in the United States have proven the relationship between taking vitamin B 9 preparations and the progression of colon tumors.

Since 1980, Harvard has conducted a survey every 2 years, in which approximately 90,000 women with children participated. The questions concerned nutrition and, separately, the intake of vitamin complexes. In 1994, the collected information was carefully examined for the incidence of colon cancer, the third most common cancer among women in the United States. Survey data showed that women who took sufficient amounts of vitamin B 9 - more than 0.4 g mg per day, were least likely to suffer from this disease.

Scientists concluded: 75% of cases of colon tumors in women can be avoided if prophylactic doses of vitamin B 9 are consumed throughout life.

Research has led to another important conclusion. Least of all, a tumor of the large intestine occurred in women who regularly consumed vitamin complexes over the past 10-15 years.

Folic acid and prevention of atherosclerosis

Recently, doctors are increasingly inclined to believe that folic acid is effective in the prevention of atherosclerosis, the main factor in diseases of the cardiovascular system.

Today, a new theory of the pathogenesis of atherosclerosis is popular in Western countries. According to this theory, the main reason for the progression of atherosclerosis is the high level in the blood of cholesterol, which is not known to everyone, but another bioactive factor - homocysteine.

Homocysteine ​​is an endogenous amino acid. Under the influence of enzymes in the body, it is transformed into the essential fatty amino acid methionine, which is involved in the production of protein. If the body is deficient in the appropriate enzymes, homocysteine ​​accumulates in the blood and destroys the walls of blood vessels, causing inflammation. Cholesterol is involved in this process at later stages. Supporters of the new theory argue that without homocysteine, even with an elevated level of cholesterol in the blood, atherosclerosis does not progress.

What is the role of folic acid in this vein? The fact is that it is it that is necessary for the synthesis in the body of enzymes that transform homocysteine ​​into methionine. Deficiency of vitamin B 9 causes a deficiency of the corresponding enzyme. As a result, excess homocysteine ​​accumulates in the blood, which leads to the progression of atherosclerosis, and then to its complications - ischemia of the heart muscle, heart attack, stroke.

There are contraindications. Before use, you should consult with a specialist.

People have known about the benefits of vitamin B9 (folic acid) for a long time, but only relatively recently, doctors began to actively promote the use of this substance among the population. Folic acid is prescribed during the period of bearing a child, it is included in complex therapy in the treatment of heart disease, there is a lot of controversy about how this vitamin is capable of provoking the development of cancer or it is an inhibitory factor in the growth of cancer cells. Only one thing is indisputable - folic acid is needed by the body of every person, but its intake is especially important for women.

Features of folic acid

The benefits of vitamins and minerals are known to all. Many of us know what calcium and magnesium are, why iron is needed in the body, and what effect vitamins B6, B12, A and C, PP and D have. Vitamin B9, folic acid, in which the active substance is folate, remains undeservedly forgotten.

Note:folic acid cannot be produced by the body itself, and its ability to accumulate in tissues and organs is zero. Even if a person introduces the maximum amount of foods containing vitamin B9 into his diet, the body will absorb less than half of the original volume. The main disadvantage of folic acid is that it destroys itself even with a slight heat treatment (storage of the product in a room with room temperature is enough).

Folates are a fundamental component in the process of DNA synthesis and maintaining its integrity. In addition, it is vitamin B9 that contributes to the production of specific enzymes by the body, which are actively involved in the prevention of the formation of malignant tumors.

The lack of folic acid in the body was detected in people aged 20-45 years, in pregnant and lactating women. This can lead to the development of megaloblastic anemia (oncology associated with a decrease in DNA synthesis), the birth of children with developmental defects. There are also certain clinical symptoms indicating a lack of folic acid in the body - fever, often diagnosed inflammatory processes, disorders in the digestive system (diarrhea, nausea, anorexia), hyperpigmentation.

Important:natural folic acid is absorbed much worse than synthetic: taking 0.6 μg of a substance in the form of a medication is equal to 0.01 mg of folic acid in its natural form.

How to take folic acid

The National Academy of Sciences in 1998 published a general instruction on the use of folic acid. The dosage according to these data will be as follows:

• optimal - 400 mcg per day per person;
• minimum - 200 mcg per person;
• during pregnancy - 400 mcg;
• during lactation - 600 mcg.

note: in any case, the dosage of vitamin B9 is set on an individual basis and the above values ​​can only be used for a general understanding of the daily dosage of the drug. There are clear restrictions on the daily amount of the substance under consideration when planning pregnancy and during the period of bearing / feeding a child, as well as in the case of the use of folic acid for the prevention of cancer.

Folic acid and pregnancy

Folic acid is responsible for DNA synthesis, it is actively involved in cell division, in their restoration. Therefore, the drug in question must be taken both during pregnancy planning, and during the period of bearing a child, and during breastfeeding.

Folic acid is given to women who have stopped taking birth control and are planning a baby. It is necessary to start using the substance in question as soon as the decision is made to conceive and give birth to a child - the importance of the absolute abundance of folic acid in the mother's body in the first days / weeks of pregnancy is difficult to assess. The fact is that at the age of two weeks, the brain is already beginning to form in the embryo - at this time, a woman may not be aware of pregnancy. In the early stages of pregnancy, the baby's nervous system is also formed - folic acid is necessary for proper cell division and the formation of an absolutely healthy body. Why do gynecologists prescribe vitamin B9 to women when planning a pregnancy? The substance in question takes an active part in hematopoiesis, which occurs during the formation of the placenta - with a lack of folic acid, pregnancy can result in a miscarriage.

A lack of folic acid in a woman's body during her pregnancy can lead to the development of birth defects:

• "hare lip";
• hydrocephalus;
• "cleft palate";
• neural tube defect;
• violation of the mental and intellectual development of the child.

Ignoring folic acid prescriptions from a gynecologist can lead to premature birth, placental abruption, stillbirth, miscarriage - according to scientific studies, in 75% of cases, this development can be prevented by taking folic acid 2-3 months before pregnancy.

After childbirth, it is also not worth interrupting the course of taking the substance in question - postpartum depression, apathy, general weakness are the result of a lack of folic acid in the body of the mother. In addition, in the absence of additional introduction of folates into the body, there is a deterioration in the quality of breast milk, its quantity decreases, which affects the growth and development of the child.

Dosage of folic acid during pregnancy and lactation

During the period of planning and carrying a pregnancy, doctors prescribe folic acid to a woman in the amount of 400-600 mcg per day. During breastfeeding, the body needs a higher dosage - up to 600 mcg per day. In some cases, women are prescribed a dose of 800 micrograms of folic acid per day, but only a gynecologist should make such a decision based on the results of the examination of the woman's body. An increased dosage of the substance in question is prescribed for:

• Diabetes mellitus and epilepsy diagnosed in a woman;
• existing congenital diseases in the family;
• the need to constantly take medications (they make it difficult for the body to absorb folic acid);
• the birth of earlier children with a history of folate-dependent diseases.

Important : in what quantities a woman should take folic acid during the periods of planning / bearing pregnancy and lactation, the gynecologist should indicate. It is strictly forbidden to choose a “convenient” dosage on your own.

If a woman is absolutely healthy, then vitamin B9 is prescribed in the form of multivitamin preparations that a woman needs when planning a pregnancy and bearing a child. They are sold in pharmacies and are intended for expectant mothers - Elevit, Pregnavit, Vitrum Prenatal and others.

If the need for an increased dosage of folic acid is identified, a woman is prescribed drugs with a high content of vitamin B9 - Folacin, Apo-Folic.

note: to know exactly how many capsules / tablets to take per day, you need to study the instructions for the drug and get advice from a gynecologist.

The principle of using preparations containing folic acid is simple: before or during meals, drinking plenty of water.

Overdose and contraindications

Recently, it has become "fashionable" to prescribe folic acid to pregnant women in the amount of 5 mg per day - apparently, they want to fill the body with vitamin B9 for sure. This is absolutely wrong! Despite the fact that excess folic acid is excreted from the body 5 hours after intake, an increased dosage of folic acid can lead to the development of anemia, increased excitability, kidney dysfunction, and disorders of the gastrointestinal tract. It is believed that the maximum allowable dose of folic per day is 1 mg, 5 mg per day is a therapeutic dose that is prescribed for diseases of the cardiovascular system and other parts of the body.

Should be clarified : even with an overdose of folic acid as prescribed by a doctor, there is no negative effect on the intrauterine development of the fetus. Only the body of the expectant mother suffers.

A contraindication to the appointment of folic acid is an individual intolerance to the substance or hypersensitivity to it. If such a disorder was not detected before the appointment, then after taking preparations with vitamin B9, a rash and itching on the skin, facial flushing (redness), and bronchospasm may appear. If these symptoms appear, you should immediately stop taking the prescribed drugs and inform your doctor about it.

The benefits of folic acid for pregnant women are described in detail in the video review:

Folic acid in foods

Folic acid and cancer: evidence from official studies

Many sources indicate that folic acid is prescribed in the treatment of cancer. But on this occasion, the opinions of scientists / doctors are divided - some studies confirm that it is this substance that can inhibit the growth of cancer cells and serve as a preventive measure in oncology, but others have indicated the growth of malignant tumors when taking drugs with folic acid.

Overall Cancer Risk Assessment with Folic Acid

The results of a large study assessing the overall risk of developing cancer in patients taking folic acid supplements were published in January 2013 in The Lancet.

“This study provides confidence in the safety of taking folic acid for a period not exceeding five years, both in the form of supplements and in the form of fortified foods.”

The study involved about 50,000 volunteers, who were divided into 2 groups: the first group was regularly given folic acid preparations, the other group was given a placebo "dummy". The folic acid group had 7.7% (1904) new cases of cancer, while the placebo group had 7.3% (1809) new cases. A marked increase in the overall incidence of cancer was not seen even in people with a high average intake of folic acid (40 mg per day), experts say.

Risks of developing breast cancer when taking folic acid

In January 2014, the results of another study were published. Scientists have studied the risks of developing breast cancer in women taking folic acid. Canadian researchers at St. Michael's Hospital in Toronto, including Dr. Yong-In-Kim, lead author of the study, found that folic acid supplements taken by breast cancer patients can promote the growth of malignant cells.

Previously, some scientists argued that folate is able to protect against various types of cancer, including breast cancer. However, studies by Canadian scientists have shown that folic acid intake at a dosage of 2.5 mg 5 times a day for 2-3 consecutive months significantly contributes to the growth of existing precancerous or cancerous cells in the mammary glands. rodents. Important: this dosage is many times higher than the dosage recommended for humans.

Folic acid and prostate cancer risks

In March 2009, the Journal of the National Cancer Institute published the results of a study of the relationship between folic acid intake and the risk of developing prostate cancer.

Scientists from the University of Southern California, in particular, study author Jane Figueiredo, found that taking vitamin supplements with folic acid more than doubles the risk of developing prostate cancer.

The researchers followed the health status of 643 male volunteers for more than six and a half years, with an average age of about 57 years. All men were divided into 2 groups: the first group received folic acid (1 mg) daily, the second group was given a placebo. During this time, 34 study participants were diagnosed with prostate cancer. Based on their data, scientists calculated the likelihood of developing prostate cancer in all participants for 10 years and came to the conclusion that 9.7% of people from the 1st group (taking folic acid) and only 3.3% can get cancer. men from the second group (taking "pacifiers").

Folic acid and throat cancer

In 2006, scientists at the Catholic University of the Sacred Heart found that taking large doses of folic acid helps regress leukoplakia of the larynx (a precancerous disease that precedes cancer of the larynx).

The experiment involved 43 people who were diagnosed with leukoplakia of the larynx. They took 5 mg of folic acid 3 times a day. The results of the study, published by its leader Giovanni Almadori, surprised physicians: regression was recorded in 31 patients. In 12 - a complete cure, in 19 - a decrease in spots by 2 or more times. Italian scientists analyzed and found that in the blood of patients with head and neck cancer, as well as patients suffering from laryngeal leukoplakia, the concentration of folic acid is reduced. Based on this, a hypothesis was put forward about a low level of folate as a provoking factor in the development and progression of oncological diseases.

Folic acid and colon cancer

Previously, scientists from the American Cancer Society proved that vitamin B9 significantly reduces the risk of development - it is enough to consume folic acid in the form of natural products (spinach, meat, liver, animal kidneys, sorrel) or synthetic preparations.

Tim Byers found that patients who took dietary folic acid supplements had an increase in the number of polyps in the intestines (polyps are considered precancerous conditions). Important: the scientists emphasized that we are talking about the use of drugs, and not products containing folates.

Note: most of the studies confirming the increased risk of malignant neoplasms are based on taking doses many times higher than the minimum recommended. Remember that the recommended dose is 200-400 micrograms. Most folic acid preparations contain 1 mg of folate, which is 2.5 to 5 times the daily value!

Tsygankova Yana Alexandrovna, medical observer, therapist of the highest qualification category

Folic acid, also known as vitamin B9, is one of the most important elements that is invaluable for both the expectant mother and the developing fetus inside her. The substance in question takes part in the production of DNA cells and blood elements, reduces the likelihood of developing various kinds of defects and pathologies, and contributes to the formation of a healthy placenta.

After reviewing the information below, you will find out in what quantities you need to take folic acid and get a generally complete picture of the substance in question.

Folic acid deficiency: why is it dangerous?

During pregnancy, an insufficient content of vitamin B9 in the maternal body can lead to the development of pathologies of the fetal nervous system, for example, hydrocephalus, and in exceptional cases even anencephaly. Sometimes there are formation of cerebral hernias, problems with the physical and mental development of the baby, etc.

In view of this, folic acid must be present in the body of the expectant mother in sufficient quantities. You are invited to read the detailed information on this subject below.

Folic acid in questions and answers

For greater ease of perception, information on folic acid has been prepared in the format of questions and answers and is presented in the form of a table.

Table. Folic acid in questions and answers

Question	Answer
Why take folic acid?	This substance contributes to the normalization of the processes of growth and development of the fetus, especially in the initial stages. With a lack of vitamin B9, as noted, the likelihood of various kinds of congenital malformations increases significantly.
Who needs to take folic acid?	According to statistics provided by medical institutions, every second woman has an insufficient amount of folic acid in the body. The risk group includes patients who drink alcohol and take hormonal drugs.
When is vitamin B9 most important?	The greatest need for folic acid is noted during the first 4 weeks after conception - during this time the neural tube of the fetus is formed.
How to increase the content of folic acid in the body?	Experts recommend taking folic acid daily 3-6 months (the specific period is set by the doctor) before the planned conception, as well as throughout the entire pregnancy.
Who should take vitamin B9?	As a rule, doctors prescribe folic acid for every pregnant woman, regardless of the characteristics of her diet and other such points. Patients who have previously given birth to children with abnormalities caused by folic acid deficiency in the body are usually given an increased dosage. In general, all these issues are dealt with by a qualified specialist.
Is it possible to overdose on vitamin B9?	It has been established that for the occurrence of pronounced manifestations of an overdose, a person must take about 20-30 tablets of folic acid per day. With slight excesses of the norm, the kidneys simply remove the excess substance from the body unchanged.
Should men take folic acid?	A lack of folic acid can lead to a decrease in the number of healthy and healthy sperm in men. In view of this, at least 3 months before the planned conception, men are also recommended to start taking vitamin B9, while the concentration should not be less than prophylactic, i.e. from 0.4 mg per day.

How much folic acid to drink: recommended dosages

All over the world adhere to the dosage of 0.8 mg per day. In some cases, the dose can be significantly increased - up to 3-4 mg. It is important to understand that specific values ​​​​under any circumstances should be selected by a qualified specialist, taking into account the individual characteristics of the patient.

Folic acid is sold in tablets, each of which most often contains 1 mg of the necessary substance. That is, one tablet contains a little more than the minimum daily dose. In general, doctors in most cases recommend that women planning a pregnancy drink up to 3-4 mg of folic acid per day, so there will be no problems with the convenience of distributing vitamin B9 during the day.

How to take folic acid correctly?

Pregnancy planning should be approached with the utmost responsibility and care.

1. First, beforehand, both the man and the woman undergo the necessary examinations to establish the presence of diseases that pose a threat to future pregnancy.
2. Secondly, at least a few months before the planned conception, both future parents must stop smoking - in this case, this habit is doubly harmful, because. Under the influence of nicotine, the structure of folic acid is destroyed. Alcohol is also excluded.
3. Thirdly, you need to get rid of any kind of acute inflammation and infection, treat chronic ailments, and eliminate oral problems.

Now directly about folic acid. Based on the results of the necessary tests, a specialist who helps the couple plan a pregnancy determines the need for vitamin B9 and makes objective assumptions about its impact on the health of the developing fetus. In accordance with the individual characteristics of a particular couple, the doctor selects the optimal dosage of folic acid. For the future, the specialist will definitely prescribe additional consultations and examinations, according to the results of which the dosage of folic acid will be changed if necessary.

As noted, folic acid should be taken at least 3 months before the planned conception. This will not only increase the likelihood of successful fertilization, but also significantly increase the chances of having a full-fledged child without deviations.

Can folic acid be obtained from food?

The substance in question is found in some products. It is relatively abundant in such products as: beans, citrus fruits, chicken eggs, sorrel, nuts, oatmeal, sea fish, buckwheat, spinach, cilantro, dill, almonds, cheese, liver and kidneys (chicken, beef, pork). It is recommended to cook the liver so that it is not very fried. Greens are best eaten in the form of fresh salads - with additional cooking, the concentration of folic acid is significantly reduced.

The lack of certain substances in the human body leads to health problems. Not only vitamins C, E, A, but also folic acid perform their functions. For men, when planning a pregnancy, this substance is just as important as for expectant mothers. Useful must be included in the diet of people of all ages.

What is folic acid?

Everything in nature needs updating. In autumn, the leaves of the trees fall, and new ones come in their place in the spring. The same thing happens with the human body. Cells are updated regularly. If a person eats properly, happens a lot in the fresh air and sleeps at least 8 hours a day, all processes proceed without failures, the immune system works at full strength. But the wrong lifestyle leads to a deficiency of vitamins. Water-soluble B 9 - folic acid is responsible for the development of new cells. For men, when planning a pregnancy, the substance plays an important role.

Scientists have found that a lack of vitamin B 9 in the body can lead to disruption of the bone marrow. Red blood cells are no longer produced in the right amount. As a result, anemia occurs, the result of which will be a number of concomitant diseases. Thus, we can conclude that the daily diet should be saturated with vitamins and microelements necessary for health. We must not forget about folic acid.

grown men?

It is so inherent in nature that the male body must constantly be ready for conception. This is the difference between a gentleman and the weaker sex. The egg in women matures only once a month. But spermatozoa in men are formed constantly, regardless of the time of year and day of the week. If a couple cannot conceive a child for a long period, the question arises: is everything in order with the health of the representative of the stronger sex? Be sure to check the quality of sperm. when planning a child plays an important role. A lack of vitamin B 9 can lead to a decrease in the number of viable spermatozoa.

The lack of the right amount of folic acid in the body often contributes to the development of gene mutations. If both in a couple take vitamins before conception, this significantly increases the chances of a healthy baby being born. Both a man and a woman should start drinking folic acid no later than 3 months before the intended conception.

Folic Acid for Teenage Boys

Vitamin B 9 is responsible for the formation of new cells. In some cases, folic acid is also prescribed for teenage boys. For men with infertility, the drug is prescribed in an increased dosage. For boys, vitamin medicine can be used to regulate spermatogenesis. If a teenager has violations in this area, it will be possible to correct the situation much more effectively at an early age. If you let the problem take its course, the chances of not curing infertility increase at all.

This does not mean at all that a boy should take folic acid preparations from an early age. No pills can be given to a child without a doctor's recommendation. All parents need to do is to monitor their son's lifestyle. He should regularly be in the fresh air, eat well, sleep enough. It is necessary to seek help if the child lags behind in physical development from his peers. Most likely, in this case, the boy will be prescribed folic acid in combination with hormonal drugs. For men, when planning pregnancy, vitamin B 9 tablets are also prescribed. Although you can replace the pharmacy drug with foods rich in folic acid.

What should be included in the daily diet when planning conception?

If you use the right products, there will be no need to take pharmaceutical products. Where is folic acid found? For men, when planning a pregnancy, meat must be included in the diet. This product is considered a storehouse of various vitamins and minerals. Most folic acid is found in beef. If you eat at least 200-300 g of this product daily, the need for the use of drugs containing B 9 will disappear.

All people, regardless of age, should eat pork or beef liver. It also contains folic acid for men. When planning pregnancy, the dosage can be 100-150 g per day. It is worth supplementing the diet with other foods containing vitamin B 9. Always in the composition of dietary supplements for "male power" includes brewer's yeast. They also contain enough folic acid for men when planning a child. Reviews show that the use of multivitamin preparations is not mandatory if the family diet is rich. Both partners should eat right.

Speaking about brewer's yeast, many representatives of the stronger sex can remember beer. But in fact, those who are planning to conceive a child will have to forget about alcohol. Beer is a real sperm killer. Indeed, folic acid is found in the foamy drink. But a beneficial effect on the body is not to be expected.

folic acid tablets

Any pharmaceutical preparations cannot be an alternative to a good diet. But if for a long time it is not possible to conceive a child, a specialist may prescribe a medicine in tablets. How much folic acid should be contained in one tablet for men when planning a pregnancy (mg)? This question is very important. After all, pharmacies offer drugs with different dosages: from 0.5 to 5 mg. Tablets allow you to more accurately calculate the amount of folic acid consumed per day. Before you start taking the medicine, you should consult your doctor. In most cases, the specialist will prescribe the minimum dosage, while recommending enriching your diet with foods containing folic acid in sufficient quantities.

Indications for the use of tablets

When planning conception, folic acid for men may not always be prescribed. Reviews of experts show that a number of concomitant diseases serve as the reason for using the tablet preparation. The first is macrocytic anemia. Also, the representatives of the stronger sex are prescribed a medicine if infertility was previously diagnosed, even if the quality of the sperm is currently at a high level.

Boys during puberty are prescribed folic acid if there is a developmental delay. Vitamin B 9 stimulates spermatogenesis. For some sexual dysfunctions, folic acid can also be prescribed in combination with other drugs. For men, when planning pregnancy, the dosage is chosen exclusively by the doctor. For children, the vitamin helps to stimulate memory and the functioning of the nervous system. Therefore, the drug can be used to treat hyperactive babies. Although in this case, therapy has nothing to do with reproductive function.

How should you take folic acid?

It would seem that all that is worth paying attention to when folic acid is prescribed for men when planning a pregnancy is the dosage. Reviews of experts show that it is also necessary to choose the right time to take the drug. It is impossible to eat a tablet after a meal, washing it down with a sufficient amount of water. It is a fat-soluble substance, so it is better to drink the capsule during a meal. In addition, vitamin B 9 is absorbed in direct proportion to vitamin B 12. And if you additionally use foods rich in ascorbic acid, all B vitamins are perfectly absorbed.

We must also not forget that folic acid does not have the ability to accumulate in the body. Therefore, it is worth starting taking the drug a few months before conception and not missing a single day until the onset of pregnancy. Women should continue taking the drug throughout the entire period of bearing a baby.

What should be the dosage?

If it is impossible to replenish with the help of the diet, it is worth purchasing the drug. It is advisable to take it on the recommendation of a doctor. For each specific situation, the dosage of the drug will be different. Men who plan to conceive are prescribed 200 mcg per day.